摘要
目的分析住院2型糖尿病患者合并甲状腺疾病的患病情况和临床特点。方法回顾性分析487例住院2型糖尿病患者甲状腺功能、抗体及甲状腺B超等甲状腺相关疾病的临床资料。结果 22.18%的住院2型糖尿病患者中存在甲状腺功能异常,其中亚临床甲状腺功能减退(亚临床甲减)11.09%,甲状腺功能减退(甲减)6.98%,甲亢3.29%,亚临床甲亢0.82%。207例2型糖尿病患者行甲状腺超声检查,甲状腺结节患病率47.3%,171例检测甲状腺抗体(TPOAb或Tg Ab)阳性率为28.7%。女性2型糖尿病患者甲状腺疾病患病率、亚临床甲减患病率、甲状腺结节及甲状腺抗体阳性率明显高于男性(P<0.05)。与单纯2型糖尿病组比较,2型糖尿病合并甲状腺疾病(DM-T组)糖尿病病程、BMI、血脂及TSH水平较高,差异有统计学意义(P<0.05)。结论 2型糖尿病患者甲状腺功能异常及甲状腺结节患病率均高,尤其女性患者,故对于2型糖尿病患者常规筛查甲状腺疾病十分必要。
Objective To analyze the prevalence and clinic characters of thyroid disease in type 2 diabetic patients. Methods The clinical data of retrospective study in thyroid disease was carried out among 487 patients with type 2 diabetic patients. Results The prevalence rate of patients with type 2 diabetes in abnormal thyroid function was 22.18%. In which, subclinical hypothy- roidism was 11.09%, hypothyroidism was 6. 98%, hyperthyroidism was 3.29% and subclinical hyperthyroidism was 0. 82%. Thyroid ultra- sonography was carried out in 207 type 2 diabetes and the prevalence rate of thyroid nodule was 47.3%. The positive rate of thyroid - related antibodies was 28.7% in 171 cases with type 2 diabetes. In type 2 diabetes, the prevalence rate of thyroid disease, subclinical hypothy- roidism, thyroid nodule and thyroid antibodies in female were higher than that in male （P 〈 0.05 ）. Compared with type 2 diabetic group, type 2 diabetic patients complicating thyroid disease showed that the diabetic course, BMI, cholesterol levels and TSH levels were increased. Conclusion The prevalence rate of thyroid disease in patients with type 2 diabetes is high, especially in female. So it is im- portant to screen the thyroid disease in patients with type 2 diabetic.
出处
《宁夏医学杂志》
CAS
2016年第9期795-797,共3页
Ningxia Medical Journal
