通瘀煎化裁对瘀血阻络型2型糖尿病患者血清hs-CRP的影响

Effect of Tongyu Cutting Decoction on Blood Stasis Type hs-CRP in Serum of Patients with Type Ⅱ Diabetes

目的:探究通瘀煎化裁治疗瘀血阻络型2型糖尿病的临床疗效及对患者血清hs-CRP的影响。方法:选择到我院就诊的中医辨证为瘀血阻络型2型糖尿病患者60例,随机分为对照组和观察组各30例。两组均予糖尿病常规治疗,并口服阿司匹林肠溶片,疗程4周,观察组另加服通瘀煎化裁。结果:观察组hs-CRP、中医症候积分改善程度均明显优于对照组,总有效率明显高于对照组。结论:通瘀煎化裁可明显改善患者临床症状,减低瘀血阻络型2型糖尿病患者的hs-CRP值,从而减少体内慢性炎症反应,改善胰岛素抵抗,延缓糖尿病的进展。

Objective：To explore the clinical curative effect and the hs-CRP in Serum of Tongyu Cutting Decoction on blood stasis type in patients with type II diabetes. Methods：60 cases of blood stasis type in patients with type II diabetes were randomly assigned to con-trol group and treatment group with 30 cases in each group according to syndrome differentiation in TCM treatment in our hospital. The two groups were given conventional treatment of diabetes and oral aspirin enteric coated tablets. In the treatment group, the treatment group was treated with Tongyu Cutting Decoction for 4 weeks. Results：The hs-CRP and TCM syndrome score of the treatment group were significantly better than that of the control group, and the total effective rate was significantly higher than that of the control group. Conclusion： Tongyu Cutting Decoction can improve the clinical symptoms of patients obviously and reduce the hs CRP of blood stasis type in patients with type II diabetes to reduce chronic inflammatory response in vivo, improve insulin resistance and delay diabetes progression.