摘要
性别决定区Y框18[SRY(sex determining region Y)-box 18,SOX18]是一种转录因子,属于SRY相关基因,常表达于生长中的脉管系统,参与血管、淋巴管发育过程,其基因突变或异常表达与许多体内肿瘤发生发展有关。
SOX18 ,a member of the SOX gene family ( SRY-like 3-hydroxy-3-nlethylglutaryl box gene) ,is a transcription factor expressed in the development of the vascular system, which is involved in the regulation of blood vessels and lymphatic vessels development. SOX18 gene mutation or abnormal expression is related to tumorigenesis.
出处
《济宁医学院学报》
2016年第4期280-282,287,共4页
Journal of Jining Medical University
基金
济宁医学院青年基金项目(编号:JYQ 2011KM 018)