青年脑梗死危险因素Logistic回归分析

Logistic Regression Analysis of Risk Factors of Youth Cerebral Infarction

目的分析青年脑梗死发病的危险性因素,为制定控制措施提供指导方法。方法回顾性分析将汕头市中心医院于2000年1月至2013年12月住院部收治的首次发病的1389例青年脑梗死患者的临床资料,将青年脑梗死患者作为观察组,同期选择在我院健康体检中心健康体检的年龄在18~49岁青年1200例非脑梗死体检者作为对照组,分别采用单因素分析及多因素Logistic分析模型探讨青年脑梗死发病的危险性因素。结果多因素分析表明男性（OR=3.604,95%CI：0.916~15.721）、高血压（OR=12.305,95%CI：2.219~49.709）、糖尿病（OR=3.155,95%CI：0.829~13.081）、TG增高（OR=2.583,95%CI：0.482~9.620）、TC增高（OR=2.795,95%CI：0.718~11.360）、Ldl增高（OR=5.094,95%CI：0.921~26.720）、Hdl降低（OR=5.646,95%CI：1.028~31.860）、吸烟史（OR=4.513,95%CI：0.814~23.509）、饮酒史（OR=3.267,95%CI：0.861~15.708）及房颤（OR=7.330,95%CI：1.421~37.530）为青年脑梗死患者发病的危险性因素。结论青年脑梗死发病危险因素较多,应加强对可控因素的干预,降低脑梗死的发病率。

objective Analysis the risk factors of Youth cerebral infarction,to provide guidance for the development of control measures. Methods Retrospective Analysis 1389 Youth cerebral infarction clinical data in Shantou Central Hospital from January2000 to December 2013.Defined Youth cerebral infarction as the observation group,and choose 1200 cases age of 18-49 years noninfarct Youth volunteers from our examination center in our hospital as the control group. the univariate analysis and multivariate Logistic regression model were used to explore the risk factor of youth cerebral infarction. Results Multivariate analysis showed that males（OR=3.604,95% CI： 0.916-15.721）,hypertension（OR=12.305,95% CI： 2.219-49.709）,diabetes（OR=3.155,95% CI：0.829-13.081）,TG increased（OR = 2.583,95% CI： 0.482-9.620）,TC increased（OR=2.795,95% CI： 0.718-11.360）,ldl increased（OR=5.094,95% CI： 0.921-26.720）,hdl reduced（OR=5.646,95% CI： 1.028-31.860）,smoking history（OR=4.513,95%CI： 0.814-23.509）,drinking history（OR=3.267,95% CI： 0.861-15.708）and atrial fibrillation（OR=7.330,95% CI： 1.421-37.530）are the risk factor for Youth cerebral infarction. Conclusion There are lots risk factors of Youth cerebral infarction.the Controllable factors should be strengthen interventions,and reduce the incidence of cerebral infarction.