内镜黏膜下剥离术治疗早期食管癌远期疗效的研究进展

Research advances on long-term outcomes of endoscopic submucosal dissection for early esophageal cancer

随着内镜技术的创新提高,越来越多的早期食管癌在内镜检查中被发现.无论食管癌病灶的大小及黏膜下纤维化的有无,内镜黏膜下剥离术可达到病灶的整块切除及组织学上的完全切除,已成为早期食管癌更优的治疗选择.目前,早期食管癌内镜黏膜下剥离术的短期疗效显著,但长期预后研究不足.通过对早期食管癌内镜黏膜下剥离术后狭窄、复发、转移、生存率的随访进行综述,为临床医师提供参考.

With the improvement of endoscopic technology,an increasing number of early esophageal cancer is diagnosed by gastroscopy.Regardless of the size or submucous fibrosis of esophageal cancer,endoscopic submucosal dissection （ESD） allows en bloc resection and histologically complete resection of the tumor.ESD has been recognized as an optimal treatment modality for early esophageal carcinoma.Currently,short-term curative effects of early esophageal cancer after ESD have been proved satisfactory,but the long-term outcomes remain unclear.This paper reviews the research advances about the long-term outcomes of ESD,and focuses on the postoperative stenosis,the recurrence,metastasis and survival rates of patients,to provide treatment reference for clinicians.