摘要
Biomaterials are increasingly being evolved to actively adapt to the desired microenvironments so as to introduce tissue integration, reconstruct stability, promote regeneration, and avoid immune rejection. The complexity of its mechanisms poses great challenge to current biomimetic synthetic materials. Although still at initial stage, harnessing cells, tissues, or even entire body to synthesize bioadaptive materials is introducing a promising future.
Biomaterials are increasingly being evolved to actively adapt to the desired microenvironments so as to introduce tissue integration, reconstruct stability, promote regeneration, and avoid immune rejection. The complexity of its mechanisms poses great challenge to current biomimetic synthetic materials. Although still at initial stage, harnessing cells, tissues, or even entire body to synthesize bioadaptive materials is introducing a promising future.
基金
supported by the National Basic Research Program of China(973 Program,No.2012CB619105)
the China Postdoctoral Science Foundation(Nos.2013M531876 and 2014T70826)
the National Natural Science Foundation of China(Nos.31430030,81272041,81071512 and 31170902)
the Natural Science Foundation of Guangdong Province(Nos.2014A030310466 and 2013B060300007)
the Foundation of Shenzhen Committee for Science and Technology Innovation(Nos.CXZZ20130516103023168 and 2015-336,2013-950)
the Jiangxi Province Science and Technology Support Plan Project(No.2010BSA14800)
the Guangdong Provincial Key Laboratory of Orthopaedics and Tranmstology
