等离子双极电切术治疗良性前列腺增生的临床研究

Clinical study of plasma bipolar TURP in treating benign prostatic hyperplasia

目的研究等离子双极电切术改善良性前列腺增生血、尿流动力学的效果。方法选择本院2014年1月~2015年3月住院的良性前列腺增生患者50例（观察组）,另选30例健康体检者为正常组。观察组采用等离子双极电切术,分析两组血流动力学的最大血流速度（Vmax）、最小血流速度（Vmin）、阻力指数（RI）、尿流动力学最大尿流率（MFR）,平均尿流率（AFR）,最大后尿道压（MPUP）,最大尿道闭合压（MUCP）。应用国际前列腺症状评分（IPSS）、生活质量（QOL）评分评价患者术后的生活质量。结果观察组患者术前Vmax、Vmin、RI与正常组比较,差异有统计学意义（P〈0.05,P〈0.01）;术后观察组患者Vmax、Vmin、RI值明显较术前有所改善（P〈0.01）。尿动力学检查,术前观察组MFR、AFR、MPUP、MUCP与正常组比较,差异有统计学意义（P〈0.01）。观察组手术前后MFR、AFR、MPUP、MUCP检查结果比较,差异有统计学意义（P〈0.01）。观察组术前与手术后1个月、2个月、3个月的IPSS、QOL评分比较,差异有统计学意义（P〈0.01）。结论等离子双极电切术治疗良性前列腺增生,能明显改善患者血、尿流动力学,提高患者生活质量。

Objective To study the effect of plasma bipolar electric resection on improving the blood and urine dynamics of benign prostatic hyperplasia.Methods 50 patients with benign prostatic hyperplasia from January 2014 to March2015 hospitalized were treated by plasma bipolar resection（observition group）,and 30 healthy subjects were selected as normal group.Changes of maximum velocity（Vmax）,minimum flow velocity（Vmin）,resistance index（RI）,urodynamic maximum urinary flow rate（MFR）,average flow rate（AFR）,maximum urethral pressure（MPUP）,maximum urethral closure pressure（MUCP） between two groups were analyzed by patients′ blood and urine samples.The quality of life for patients after surgery were evaluated by international prostate symptom score（IPSS）and quality of life score（QOL）.Results Vmax,Vmin, RI of observition group before surgery were statistically significant compared with normal group,with statistical difference（P〈0.05,P〈0.01）,Vmax,Vmin,RI of observition group after surgery was significantly improved compared with before surgery,with statistical difference（P〈0.01）.MFR,AFR,MPUP,MUCP of the observition group in urodynamics before surgery was a significant difference compared with normal group respectively（P〈0.01）.MFR,AFR,MPUP,MUCP had very significant statistical significance before and after surgery（P〈0.01）.IPSS,QOL scores in a month,two months,three months after surgery was statistically significant compared with that before surgery respectively（P〈0.01）.Conclusion Plasma bipolar resection for benign prostatic hyperplasia can significantly improve the patients′ bloodstream,urodynamic and the quality of life.