妊娠期肝内胆汁淤积症的诊治研究现状被引量：6

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摘要妊娠期肝内胆汁淤积症（intrahepatic cholestasisof pregnancy,ICP）是妊娠期重要的产科并发症,常见于妊娠的中、晚期,具有一定遗传易感性,通常主要表现为手足瘙痒和血中胆汁酸增高的症状.此病为排除性诊断,通常预后较好,但对于胎儿的影响可能是致命的如胎儿窘迫,死胎和新生儿窒息等.由于该病的具体发病机制尚不明确,对于该疾病的早期诊断、及时治疗尚缺乏国际诊疗指南,因此研究该病的临床诊断治疗的最新研究现状为临床实践提供指导具有重要意义.本文就妊娠期肝内胆汁淤积症的现阶段临床诊断治疗的研究现状加以阐述.

作者冯娟

机构地区潍坊市妇幼保健院

出处《实用心脑肺血管病杂志》 2016年第B04期202-202,204,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

关键词妊娠期肝内胆汁淤积症诊断治疗

分类号 R969.4 [医药卫生—药理学]

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1王涛,刘淑芸,许良智,邢爱耘,刘关键.S-腺苷蛋氨酸改善妊娠肝内胆汁淤积症患者妊娠结局的评价[J].中国循证医学杂志,2005,5(2):130-135. 被引量：36
2徐小晶.妊娠肝内胆汁瘀积症围生期护理观察[J].中国民族民间医药,2012,21(19):133-134. 被引量：3
3贺晶,陈璐,梁琤.妊娠期肝内胆汁淤积症发生死胎的临床因素分析[J].中华妇产科杂志,2011,46(5):333-337. 被引量：52
4薛川,李绍民,徐方明,丁贤君,黎运呈,张国梁,林志益,李绍佐,张浙恩,曾芳,李世波.退黄汤联合熊去氧胆酸对α-萘异硫氰酸酯诱导的大鼠急性肝损的保护作用[J].中华中医药学刊,2013,31(2):311-315. 被引量：2
5Bin Ling,Fengqiu Yao,Ying Zhou,Zhengzheng Chen,Guodong Shen,Yuanyuan Zhu.Cell-Mediated Immunity Imbalance in Patients with Intrahepatic Cholestasis of Pregnancy[J].Cellular & Molecular Immunology,2007,4(1):71-75. 被引量：19

二级参考文献38

1陆伦根.胆汁淤积性肝病的合理用药[J].实用临床医药杂志,2007,11(3):1-3. 被引量：16
2孙红兵,梅劼,岳军,陈廉.妊娠期肝内胆汁淤积症胎儿监护与围生儿预后关系分析[J].实用妇产科杂志,2007,23(7):424-427. 被引量：30
3曹泽毅.《中华妇产科学》[M](第1版)[M].北京:人民卫生出版社,1999.500-507.
4Frezza M, Surrenti C, ManziUo G, Fiaccadori F, Bortolini M, Di Padova C, Oral S.adenosylmethionine in the symptomatic treatment of mtrahepatic cholestasis. A double-blind, placebo-controlled study[J]. Gastroenterology, 1990; 99(1 ) : 211 - 215.
5Alma.rio P, Bortolini M, Pagliaro L, Coltorti M. Role of S-adenosyl-L-methionine in the treatment of intrahepatic cholestasis [J ]. Drugs,1990; 40 (Suppl 3) : 111-123.
6Jadad AR, Moore A, Carroll D. Assessing the quality of reports ofrandomized chnical trials: Is bhnding necessary [ J ]. Control Clinical Trials, 1996; 17(1): 1-12.
7Bonessio L, Ciardo A, Spina V, Morini A. Intrahepatic cholestasis in pregnancy[J]. Clin Ter, 1996; 147(7-8) : 377 -384.
8Ribalta J, Reyes H, Gonzalez MC. S-adenosyl-L-methionine in the treatment of patients with intrahepatic cholestasis of pregnancy: a randomized, double-blind, placebo-controlled study with negative results[J]. Hepatology, 1991; 13(6): 1 084-1 089.
9Frezza M, Pozzato G, Chiesa L. Reversal of intrahepatic cholestasis of pregnancy in women after high dose S-adenosyl-L-methioninead ministration[J]. Hepatology, 1984; 4(2): 274-278.
10Floreani A, Patemoster D, Melis A, Grella PV. S-adenosyl-1-methionine versus ursodeox-ycholic acid in the treatment of intrahepatic cholestasis of pregnancy: preliminary results of a controlled trial[ J ], Eur J Obstet Gynecol Reprod Biol, 1996 ;67 ( 2 ) :109 - 113.