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化疗联合CIK在恶性肿瘤中的应用效果观察

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摘要 目的观察化疗联合细胞因子诱导的杀伤细胞(CIK)治疗恶性肿瘤的临床应用效果,并做探讨.方法选取 2012 年 10 月 -2015 年 10月本院行化疗联合CIK治疗恶性肿瘤的患者68例,制备CIK细胞,并回输到患者体内,配合化疗治疗,对比观察患者治疗前后实体瘤疗效,以及化疗是否有不良反应.结果本研究选取 68 例恶性肿瘤患者,均行化疗联合CIK治疗.经过治疗,其中3例完全缓解,9例部分缓解,45例病情稳定,8例病情进展,因治疗无效死亡患者3例,治疗有效率83.8%(57/68).患者治疗前的平均KPS评分为(9.6±1.8)分,治疗后,53例患者KPS评分较治疗前提高,平均KPS评分为(16.8±3.2)分,且差异具有统计学意义(P〈0.05);10例患者评分无明显变化.其中治疗无效死亡3例,其余患者在治疗期间,均未出现不良的临床反应.结论化疗联合CIK治疗恶性肿瘤的效果显著,安全性高,值得临床推广应用.
作者 廖小林
出处 《湖南中医药大学学报》 CAS 2016年第A01期24-24,共1页 Journal of Hunan University of Chinese Medicine
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