摘要
目的探讨微波消融对原发性肝癌患者热休克蛋白70（HSP70）、表面钙黏着糖蛋白（E-cad）的影响. 方法58例原发性肝癌患者采用微波消融治疗,检测治疗前后HSP70、 E-cad的变化. 结果微波消融治疗后, HSP70表达水平下调, E-cad的表达水平增强,差异均有统计学意义（P〈0.05）.治疗1个月后HSP70表达水平下调更为明显,差异有统计学意义（P〈0.05）.结论微波消融能够抑制HSP70表达水平、增强E-cad 表达水平,可能通过此来发挥临床作用.
ObjectiveTo investigate influence on the HSP70 and E-cad of microwave ablation in treatment of hepatocellular carcinoma. Method58 cases of hepatocellular carcinoma were treated with microwave ablation. The expressions changes of HSP70 and E-cad before and after treatment were detected. ResultThe levels of HSP70 were significantly lower after the treatment （P〈0.05）. The levels of E-cad were significantly highly after the treatment（P〈0.05）. After 1 months of treatment, the expression level of HSP70 was significantly lower. ConclusionMicrowave ablation could inhibit the expression of HSP70 and increase the expression of E-cad. Microwave ablation may be through this to play a clinical role.
出处
《湖南中医药大学学报》
CAS
2016年第A01期129-130,共2页
Journal of Hunan University of Chinese Medicine
基金
琼卫1321320.67A1006项目编号：琼卫2012pt-92.
