卡泊三醇软膏和卤米松乳膏序贯疗法治疗斑块状银屑病的疗效及安全性评价

目的探讨卡泊三醇软膏和卤米松乳膏序贯疗法治疗斑块状银屑病的疗效及安全性.方法选取我院在 2013 年 3 月-2015 年3月收治斑块状银屑病患者 96例作为实验研究对象,采用随机法分成观察组及对照组,每组各48例,给予对照组患者卡泊三醇软膏治疗,给予观察组患者卡泊三醇软膏和卤米松乳膏序贯疗法治疗,比较分析两组患者治疗效果及不良反应发生几率.结果观察组患者治疗2周、4周及6周后,三阶段的治疗有效率均显著高于对照组,差异有统计学意义;观察组患者不良反应出现几率为14.58%,显著低于对照组（37.5%）,P〈0.05.结论卡泊三醇软膏和卤米松乳膏序贯疗法对斑块状银屑病具有较好效果,不良反应出现几率低,值得使用与推广.

ObjectiveTo investigate the efficacy and safety of Calcipotriol Ointment and Halometasone Cream sequential therapy in the treatment of plaque psoriasis. Methodsthe hospital in March 2013 March 2015 were 96 cases of patients with plaque psoriasis as the research object, divided into observation group and control group by random method, 48 cases in each group, the control group was given the treatment given to Calcipotriol Ointment, Calcipotriol Ointment and Halometasone Cream in the observation group sequential therapy, comparative analysis and adverse reactions of two groups of patients with treatment effects. Resultsthe incidence of the patients in the observation group were treated for 2 weeks, 4 weeks and 6 weeks after treatment, the three phase of the effective rate was significantly higher than the control group, the difference was statistically significant; the probability of adverse reactions of the observation group as of 14.58%, significantly lower than the control group （37.5%）, Calcipotriol Ointment and Halometasone Cream P〈0.05. Conclusionsequential therapy on the spot Block psoriasis has a good effect, the adverse reaction rate is low, it is worth using and promotion.