氧驱动雾化吸入与空气压缩泵雾化吸入治疗小儿哮喘的疗效对比观察

目的：对比观察小儿哮喘采用氧驱动雾化吸入及空气压缩泵雾化吸入治疗的疗效及安全性.方法：2014年1月-2015年12月期间,选择于我院儿科住院的哮喘患儿160例,根据随机数字表法进行分组处理,每组患儿均80例,在内科常规治疗基础上,对照组患儿给予空气压缩泵雾化吸入,实验组患儿给予氧驱动雾化吸入,7d后对比两组的临床疗效及安全性差异.结果：实验组的治疗总有效率96.3%较对照组85.0%显著升高,住院及症状消失时间较对照组显著缩短,FeNO较对照组显著降低,P〈0.05,存在明显统计学差异.治疗前,两组的心率、呼吸频率及血氧饱和度无明显统计学差异,P〉0.05;治疗后,实验组的心率、呼吸频率未见显著变化,血氧饱和度显著上升,P〈0.05,存在明显统计学差异;对照组的心率较治疗前显著增加,呼吸频率及血氧饱和度未见明显变化,P〉0.05.结论：与空气压缩泵雾化吸入治疗相比,氧驱动雾化吸入对小儿哮喘治疗效果更佳,可缩短症状恢复时间,并改善缺氧及呼吸状态,因而更具应用价值.

Objective：To compare the efficacy and safety of oxygen atomizing inhalation and air compression pump atomization inhalation in children with asthma. Methods： During January 2014 and 2015 December, 160 cases of children with asthma in our hospital were selected. According to the random number table approach for packet processing,80 cases in each group. In the conventional medical treatment, the control group was treated with air compression pump inhalation,the experimental group was treated with oxygen atomizing inhalation,after 7d,contrasted the clinical curative and effect and safety differences of two groups.Results： The total efficiency of the experimental group was 96.3%,increased significantly compared with the control group 85.0% , hospitalization and the symptoms disappear time were significantly shorter than the control group,FeNO decreased significantly than the control group,P〈0.05,there was significant difference.Before treatment, the heart rate, respiratory rate and blood oxygen saturation had no significant statistical difference of two groups,P〉0.05; after treatment,the heart rate, respiratory rate had no significant changes, blood oxygen saturation increased significantly,P〈0.05,there was significant difference; compared with before treatment,the heart rate increased significantly of control group, respiratory rate and oxygen saturation had no significant changes of control group,P〉0.05.Conclusion：Compared with the air compression atomizing pump inhalation treatment,the oxygen drive atomization inhalation for asthma in children has better effect,it can short the recovery time of symptoms, and improve hypoxia and respiratory status,and has more practical value.