高血压病病性证素与年龄、肥胖及血脂的关系探析

Correlation of the Distribution of TCM Syndrome Elements with Age,Obesity and Dyslipidemia in Patients with Hypertension

目的探讨高血压病中医病性证素分布及与年龄、肥胖及血脂异常相关性。方法收集2012年—2015年本院门诊及住院高血压病病人657例,分析证素与年龄、体重指数(BMI)、腰围、血脂的关系。结果 657例病人发病年龄以40岁以上为主,阳虚组年龄显著高于其他各组(P<0.01),呈现阳虚>气虚>血虚>风阳>阴虚>瘀血>痰浊>阳亢之规律;痰浊、瘀血组BMI显著大于血虚组,阳亢、痰浊、瘀血组腰围显著大于风阳、气虚、血虚组,肥胖、腹型肥胖发生率均以痰浊组最高(P<0.05);痰浊组总胆固醇显著高于阳虚组,痰浊、阳虚组三酰甘油显著高于血虚组,风阳组高密度脂蛋白胆固醇显著低于阳亢、痰浊、气虚、阴虚、血虚组,瘀血组亦低于血虚组(P<0.05);血脂异常以风阳、痰浊、瘀血组发生率最高。结论高血压病发病以中老年为主,阳虚组年龄最高;肥胖、腹型肥胖以痰浊、瘀血多见;血脂异常发生率以风阳、痰浊、瘀血组为高。

Objective To explore the correlation of the distribution of traditional Chinese medicine （ TCM）syndrome elements withage, obesity and dyslipidemia in patients with hypertension.Methods Six hundreds and fifty seven patients with hypertensionwerecollected in our hospital outpatient and wards from 2012 and 2015.The statistical analyses on the relationships of syndrome elementswith age, body mass index obesity （ BMI） , waist circumference and blood lipid were carried out.Results Among 657 hypertension pa -tients, the patients with a onset age of more than 40 years were more commonly seen, the average onset age in yang deficiency syn -drome group was highest and reached up to 73 years, the differences were significant compared with other groups （ P 〈0.01） .The a -ges demonstrated a discipline of yang deficiency syndrome, qi deficiency syndrome, yin deficiency syndrome, blood deficiency syn -drome, wind yang syndrome, blood stasis syndrome, turbid phlegm syndrome, yang hyperactivity syndrome in a descending order.BMI in the turbid phlegm syndrome group and blood stasis syndrome group was significantly higher than that in the blood deficiencysyndrome group.The waist circumference in yang hyperactivity syndrome group, turbid phlegm syndrome group and blood stasis syn -drome group was significantly higher than that in wind yang syndrome group,qi deficiency syndrome group and blood deficiency syn -drome group.The incidence rates of obesity and abdominal obesity were highest in the turbid phlegm syndrome group（ P 〈0.05） .To -tal cholesterol （ TC）in the turbid phlegm syndrome group was significantly higher than that in yang deficiency syndrome group.TC inthe turbid phlegm syndrome group and yang deficiency syndrome group was significantly higher than that in blood deficiency syn -drome group.high density lipoprotein cholesterol （ HDL C）in wind yang syndrome group was significantly lower than that in thegroup of yang hyperactivity syndrome group, turbid phlegm syndrome group, qi deficiency syndrome group, yin deficiency syndromegroup and blood deficiency syndrome group.HDL C in blood stasis group was also lower that that in the blood deficiency group （ P 〈0.05） .The incidence rate of dyslipidemia in wind yang syndrome group, turbid phlegm syndrome group and blood stasis syndromegroup was highest.Conclusion The hypertension mainly occurs in the middle and old age people,the average onset age in the yangdeficiency syndromegroup is highest.The obesity and abdominal obesity are more commonly seen in the turbid phlegm syndromegroup and blood stasis syndrome group.The incidence rate of dyslipidemia in wind yang syndrome group, turbid phlegm syndromegroup and blood stasis syndrome group is highest.