2015年深圳市南山区梅毒患者生存质量及其影响因素分析

Quality of life and its influencing factors in patients with syphilis in Nanshan District,Shenzhen City,2015

目的了解梅毒患者的生存质量现状及其影响因素，为提高梅毒患者生存质量及开展有效干预措施提供参考依据。方法2015年采用世界卫生组织生存质量测定量表简表（WHOQOL—BREF）对深圳市南山区归口管治的梅毒患者进行问卷调查，调查内容包括基本信息和26个生存质量测定条目，应用t检验、方差分析和非参数检验分析各相关因素对梅毒患者生存质量的影响。结果梅毒患者总的生存质量和总的健康状况得分分别为（3．23±0．73）、（2．91±0．94），均低于中国成人生存质量得分（分别为3．50±0．69、3．59±0．74），差异有统计学意义（P〈0．05）；生理、心理、社会关系和环境四个领域的得分分别是（12．60±1．74）、（12．98±2．00）、（13．91±2．55）、（12．75±2．34），除社会关系维度外，其它领域与中国常模（15．10±2．30、13．89±1．89、13．93±2．06、12．14±2．08）比较，差异均有统计学意义（P〈0．05）。社会关系领域单因素分析，高中或中专以下得分（14．19±2．49）高于大专及以上得分（13．28±2．61），女性得分（14．59±2．22）高于男性（13．28±2．69），已婚或同居得分（14．37±2．45）高于其他人群（13．29±2．57），差异有统计学意义（P〈0．05）；总的健康状况单因素分析，年龄越大（429岁、〉29～〈50岁、≥50岁得分分别是2．65±0．78、3．03±0．94、3．19±1．21），得分越高，高中或中专以下得分（3．04±0．98）高于大专及以上（2．63±0．80），已婚或同居得分（3．07±1．00）高于其他人群（2．71±0．82），差异有统计学意义（P〈0．05）。结论2015年深圳市南山区梅毒患者生存质量低于中国常模，年龄、性别、婚姻状态、学历是梅毒患者社会领域和总的健康状况得分的重要影响因素。

Objective To investigate the quality of life （QOL） and its influencing factors among patients with syphilis so as to provide evidence for improving their QOL and carrying out effective interventions. Methods A questionnaire survey was conducted with the World Health Organization Quality of Life Scale Brief Version （WHOQOL-BREF） among syphilitic patients administrated by Nanshan District, Shenzhen City in 2015. The investigation contents included general information and 26 items of QOL. Factors influencing their QOL were analyzed by t test, analysis of variance and non-parametric tests. Results The mean scores of the total QOL and general health status in the syphilitic patients were （3.23±0.73） and （2.91±0.94） respectively, which were both lower than those of Chinese adults norm （ 3.50±0.691 and （3.59±0.74） , with statistically significant differences （P 〈0. 05） The mean scores of physical, psychological and environment domains （ 12.60±1.74） , （ 12.98±2.00） and （ 12.75± 2. 34） ） of the syphilitic patients were significantly different from those of Chinese norm （ 15.10：e 2.30） , （ 13.89±1489） and （ 12. 14±2.08） , all P〈0.05）. However, the mean score of social relationship was not significantly different （ 13.91±2.55） vs. （13.93±2.06） , P〉0.05 ）. Univariate analysis of social relationship domain showed that the score of those with education level lower than high school or technical secondary school （ 14.19±2.49 ） was higher than that of those with college degree or above （ 13.28 ±2.61 ）, the score of females （ 14.59±2.22） was higher than that of males （13.28±2.69） and the score of the married or cohabitants （ 14.37± 2.45） was higher than that of the other groups （ 13.29± 2.57 ）, with statistically significant differences （ all P〈0. 05）. Univariate analysis of the general health status revealed that the older the age, the higher the scores （ the scores of the age groups of ≤ 29 years, 〉29Y〈50 years and ≥50 years were （2.65±0.78）, （3.03±0.94） and （3.19±1.21） respectively）. The score of the general health status of those with education level lower than high school or technical secondary school （3.04±0.98） was higher than that of those with college degree or above （2.63±0.80） and the score of the married or cohabitants （3.07± 1.00） was higher than that of the other groups （2.71±0.82）, with statistically significant differences （both P〈0.05）. Conclusions The QOL of patients with syphilis in Nanshan District, Shenzhen City in 2015 is inferior to that of China norm. Age, sex, marital status and educational background are important factors influencing the scores of social relationship domain and the general health of patients with syphilis.