青霉素与清利汤联用对急性肾小球肾炎患者的临床疗效评价

Clinical Efficacy of Penicillin Combined with Qingli Mixture in Patients with Acute Glomerulonephritis

目的:评价青霉素与清利汤联用对急性肾小球肾炎患者的临床疗效。方法:选取2015年6月—2016年3月医院收治的急性肾小球肾炎患者110例,将其随机分为观察组与对照组(每组55例),对照组患者给予青霉素等药物治疗,观察组患者在对照组治疗的基础上给予清利汤治疗,比较两组患者的治疗总有效率和症状消退时间。结果:观察组患者的治疗总有效率为98.18%,明显高于对照组为87.27%,经比较其差异有统计学意义(P<0.05);观察组患者的血压恢复正常时间、水肿消退时间、肉眼血尿消退时间和镜下血尿消退时间均明显短于对照组(P<0.05)。结论:青霉素与清利汤联用于治疗急性肾小球肾炎患者,其治疗总有效率明显高于单用青霉素,且患者的血压恢复正常时间、水肿消退时间、肉眼血尿消退时间和镜下血尿消退时间短。

Objective： To evaluate the clinical efficacy of penicillin combined with Qingli Mixture in patients with acute glomerulonephritis. Methods： 110 patients with acute glomerulonephritis treated during June 2015 and March 2016 were divided into observation group and control group （55 cases of each group）. The control group patients were given penicillin, while the observation group patients were given penicillin and Qingli Mixture. The total effective rate and time for symptom relief of two groups were compared. Results： The total effective rate of observation group was 98.18%, which was higher than control group of 87.27%, and the difference was statistically significant（P〈0.05）. Moreover, the time of blood pressure returning to normal, edema disappearing, gross hematuria and microscopic hematuria fade of observation group were significantly shorter than those of control group （P〈0.05）. Conclusion： The total effective rate of pa- tients treated with penicillin and Qingli Mixture was higher than that of penicillin group, moreover the the time of blood pressure returning to normal, edema disappearing, gross hematuria and microscopic hematuria fade were shorter.