罗伦特隐球菌的研究进展

Advances on Cryptococcus laurentii

近年来，随着罗伦特隐球菌个案报道的出现，临床上对这种少见的隐球菌种属越来越关注。罗伦特隐球菌感染的临床表现与新生隐球菌相仿，临床上较难鉴别。此文结合目前已有的文献报道，对罗伦特隐球菌的发病机制、流行病学、临床表现、诊治及耐药性进行综述，有助于临床医生认识该病，提高警惕性，也为临床治疗实践提供依据。

It was reported that the incidence of infection due to Cryptococcus laurentii has increased over the past years, and an increased clinical awareness of such infections appears. Clinical manifestations of Cryptococcus laurentii infections are most often indistinguishable from Cryptococcus neoformans. This article summarizes pathogenesis, characteristics of the epidemiology, clinical manifestations, as well as treatment and drug resistance of Cryptococcus laurentii infection in human, so as to help physicians understand the disease and enhance vigilance, and provide evidence to clinical practice.