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miRNA与血管新生相关细胞因子的研究进展 被引量：10

Progress of miRNA and angiogenesis related cytokines
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摘要 miRNA是在真核生物中发现的一类内源性的具有调控功能的非编码RNA,其长约20~25个核苷酸。研究表明一些miRNA在血管新生反应表现为高度表达或特异表达。miRNA参与调控心血管疾病、肿瘤、神经系统疾病、免疫系统疾病中血管新生相关细胞、细胞因子的表达,本文主要对近几年miRNA在血管新生系统中相关细胞因子的作用加以概述。 miRNAs found in eukaryotes,are non coding RNA,which have regulation function,and the size of about 20-25 nucleotides.Recently studies showed that some miRNA were highly or specifically expressed in the blood vessel.miRNAs are involved in angiogenesis and cytokine expression in cardiovascular disease,tumor,diseases of the nervous system and immune system diseases.This article reviews the role of miRNA on angiogenesis related cytokines.
作者 巩彦龙 宋敏 刘涛 董万涛 刘建鸿 李清林 孙定平
机构地区 甘肃中医药大学 甘肃中医药大学附属医院
出处 《临床心血管病杂志》 CAS CSCD 北大核心 2016年第9期877-881,共5页 Journal of Clinical Cardiology
基金 国家自然科学基金(No:81360554) 甘肃省自然科学基金计划资助项目(No:1506RJZA048)
关键词 MIRNA 血管新生 细胞因子 miRNA angiogenesis cytokines
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献34

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临床心血管病杂志
2016年 第9期

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