扁桃体肿瘤临床病理分析

Clinical Pathologic Analysis of Tonsil Tumor

目的总结原发于扁桃体的肿瘤的临床病理特点,为其临床诊断和治疗提供参考。方法回顾性分析2002年1月-2012年4月经手术切除或活体组织检查,诊断为扁桃体肿瘤的患者923例,其中恶性肿瘤810例,良性肿瘤113例。记录其肿瘤的临床表现和病理特征,以进行归纳分析。结果扁桃体肿瘤在临床上较为常见,常单侧发病,且恶性肿瘤常见。扁桃体恶性肿瘤中最常见为淋巴瘤(610例),其次为鳞状细胞癌(172例);良性肿瘤中以乳头状瘤(87例)最为常见。咽部异物感为扁桃体肿瘤最常见的首发症状。结论扁桃体肿瘤的病理类型对其诊断、治疗及预后均有重要意义。做好病理诊断与鉴别诊断,避免漏诊、误诊及不当的治疗对临床耳鼻咽喉头颈外科学医师尤为重要。

Objective To summarize the clinical pathologic features of primary tonsil tumor, in order to provide reference for its diagnosis and treatment. Methods We retrospectively analyzed the clinical data from January 2002 to April 2012, and found 810 cases of malignant tumor and 113 cases of benign tumor. The pathologic patterns and clinical manifestations of these cases were recorded for analysis. Results Most tonsil tumors were unilateral, and the malignant types were much more than the benign. The most common malignant tonsil tumors were lymphoma （610 cases）, followed by squamous cell carcinoma （172 cases）; inverted papilloma was the most common benign tumor （87 cases）. Paresthesia in the pharynx was the most common clinical manifestation that existed in almost all cases. Conclusions Tonsil tumor pathological type is very important for its diagnosis, treatment and prognosis. Laying emphasis on pathological diagnosis and differential diagnosis could avoid missed diagnosis, misdiagnosis and improper treatment, which is particularly important for clinical physicians of the otolaryngology, head and neck surgery.