我院125例艾迪注射液用药点评

Review of the Use of Aidi Injection in Our Hospital

目的:为促进临床合理使用艾迪注射液提供参考。方法:随机抽取我院2015年1-6月使用艾迪注射液的部分住院病例,就患者的性别、年龄、肿瘤发生部位、药品用法用量、溶媒种类用量、疗程、不良反应等数据应用Microsoft 2011版Excel软件进行统计和点评。结果:125例使用艾迪注射液的患者男性多于女性,平均年龄为58.4岁;66例患者(52.80%)肿瘤发生部位与说明书规定使用的适应证相符;30例患者(24.00%)使用疗程与说明书相符;溶媒种类均符合说明书推荐,但溶媒用量与说明书相符的仅6例(4.80%);单次剂量与说明书相符的有122例(97.60%);有7例发生不良反应,主要为皮疹和胃肠道反应。结论:我院艾迪注射液使用中存在着超适应证用药、使用疗程不规范、溶媒用量不适宜等问题。医师、临床药师和医院相关部门应进一步加强艾迪注射液等中药注射剂的合理使用、医嘱点评以及监督与管理,共同促进合理用药。

OBJECTIVE： To provide reference for promoting clinical rational use of Aidi injection. METHODS： Some inpa- tient records that used Aidi injection in our hospital from Jan. to Jun. 2015 were randomly selected and statistically reviewed by us- ing Excel（2011 edition） in aspects of gender, age, tumor location, usage and dosage, solvents usage, treatment course, adverse reactions, etc. RESULTS： In the 125 patients who used Aidi injection, male was more than female, with average age of 58.4 years; the tumor location of 66 patients （52.80%） was consistent with the indications in instructions; treatment course of 30 pa- tients （24.00%） was consistent with the instructions; all solvent types were consistent with the instruction recommendation, while only 6 patients （4.80%） showed consistence in solvent usage and instructions; 122 patients （97.60%） showed consistence in single dosage and instructions; 7 patients had adverse reactions, mainly rash and gastrointestinal reactions. CONCLUSIONS： The use of Aidi injection in our hospital shows off-label drug use, non-standardized treatment course and inappropriate solvent usage. Physi- cians, clinical pharmacists and relevant departments should further strengthen the rational use, medical advice comments, supervi- sion and management of Aidi injection in the hospital to promote the rational drug use.