摘要
传统的肿瘤治疗策略是寻找和消灭肿瘤。当肿瘤治疗进入精准治疗时代,肿瘤的治疗策略也转变为靶向、控制、调变和重构,即通过精确的靶向治疗,控制肿瘤的复制、血管生成以及侵袭和转移,调变肿瘤细胞进入凋亡或休眠状态,同时重构新的结构、微环境和代谢体系。治疗策略的新转变无疑将提高肿瘤患者的临床获益。
The classical treatment strategies for cancer are to seek and destroy the cancer. Along with the era of precision medicine, the treatment strategies for cancer are also transformed into targeted therapy and strategies of control, modulation and reconstruction of cancer. Through precision therapeutics, controlling replication, angiogenesis and metastasis of caner, modulating apoptosis and inducing dormancy, and reconstructing new microenvironment and metabolic systems may be promising. The change of strategies in the war on cancer may provide patients a considerable improvement of survival.
出处
《肿瘤》
CAS
CSCD
北大核心
2016年第9期1065-1069,共5页
Tumor
基金
2013年甘肃省自然科学基金项目(编号:1308RJZA181)
关键词
肿瘤
精准治疗
内科肿瘤学
Neoplasms
Precision therapeutics
Medical Oncology