摘要
老年男性患者,临床表现蛋白尿、血清肌酐轻度升高,伴有高血压,肾活检组织学改变为肾小球内皮细胞病变伴系膜溶解。该患者直肠癌术后肝脏转移,曾使用卡培他滨及贝伐珠单抗化疗。结合临床考虑贝伐珠单抗相关肾损害。
A 63-year-old man presented with proteinuria,hypertension with an increase of serum creatinine. The patient was diagnosed as liver metastasis in 2013,and underwent chemotherapy and anti-VEGF therapy. A renal biopsy showed glomerular endothelial cell lesion with mesangiolysis. The final diagnosis was glomerular disease related to bevacizumab.
出处
《肾脏病与透析肾移植杂志》
CAS
CSCD
北大核心
2016年第4期390-393,共4页
Chinese Journal of Nephrology,Dialysis & Transplantation
关键词
转移性肝癌
贝伐珠单抗
内皮细胞损伤
系膜溶解
肾活检
metastatic liver cancer
bevacizumab
endothelial cell injury
mesangiolysis
renal biopsy
