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7-脱氢胆固醇的合成工艺改进 被引量：1

Process Improvement on the Synthesis of 7-Dehydrocholesterol
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摘要 以胆固醇为原料,经酰化、氧化、还原、水解以及消除等5步反应合成维生素D3原7-脱氢胆固醇,总收率42%,其结构经1H NMR和13C NMR确证。研究了酰化反应、氧化反应、还原反应和消除反应条件对收率的影响。 7-Dehydrocholesterol,the provitamin D3,was prepared by acetylation,oxidation,reduction,hydrolysis and elimination reactions from cholesterol with 42% total yield. The structure was confirmed by1 H NMR and13 C NMR. The effects of acetylation reaction,oxidation reaction,reduction reaction and elimination reaction conditions on the yield were studied.
作者 阿尔吐克.艾沙
机构地区 新疆油田公司实验检测研究院开发实验中心
出处 《合成化学》 CAS CSCD 2016年第9期828-831,共4页 Chinese Journal of Synthetic Chemistry
关键词 胆固醇 烯丙位氧化 7-脱氢胆固醇 合成 cholesterol allylic oxidation 7-dehydrocholesterol synthesis
分类号 O624.12 [理学—有机化学]
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参考文献17

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二级参考文献32

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合成化学
2016年 第9期

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