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右美托咪啶对臂丛神经阻滞病人血流动力学的影响 被引量:6

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摘要 目的探讨右美托咪啶用于臂丛神经阻滞病人围术期镇静的临床疗效观察。方法 60例择期行尺骨和桡骨骨折切开复位内固定术的病人,性别不限,年龄16岁~60岁,体重50 kg^80 kg,ASA分级Ⅰ级或Ⅱ级,拟在超声引导下行腋路臂丛神经阻滞的病人,按随机数字表法分为3组,每组20例。A组,先右美托咪啶1μg/kg冲击量,维持10 min,然后持续泵注32μg/h。B组,右美托咪啶32μg/h持续泵注。C组,对照组。各组于手术开始前10 min开始输注。记录麻醉前(T0)、给药完成后10 min(T1)、40min(T2)、手术结束(T3)病人的平均动脉压(MAP)、心率(HR)、血氧饱和度(SpO_2)、镇静评分(Ramsay),记录各组不良反应发生情况。结果 MAP、HR在给药完成后10 min(T1)、40 min(T2),A、B组与C组组间比较差异有统计学意义(P<0.05)。MAP、HR、SpO_2在给药完成后10 min(T1)、40 min(T2)与麻醉前(T0)、手术结束(T3)比较差异有统计学意义(P<0.05)。Ramsay评分:A组、B组T1、T2时点评分高于C组(P<0.05);A组、B组组间比较各时点差异无统计学意义(P>0.05)。结论右美托咪啶用于臂丛神经阻滞病人围术期镇静效果确切、镇静满意,不良反应少,但术中要注意病人血流动力学变化。A组严重心动过缓增加,3组均未发生恶心或呕吐。
出处 《中西医结合心脑血管病杂志》 2016年第13期1560-1561,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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参考文献9

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