摘要
目的探讨非神经系统原发恶性肿瘤伴发急性脑梗死的临床特点、神经影像特点及治疗。方法收集2013年5月—2015年5月河北省唐山市人民医院收治的非神经系统原发恶性肿瘤伴发急性脑梗死患者与非肿瘤急性缺血性卒中患者的临床及神经影像学资料进行分析。结果单因素预后分析表明非神经系统原发恶性肿瘤患者并发脑梗死的影响因素有既往高血压病史(P<0.05),多因素预后分析表明肿瘤组血红蛋白、血小板计数、血栓两项、梗死病灶数为影响因素(P<0.05,P<0.01,P<0.05)。结论非神经系统原发恶性肿瘤伴发急性脑梗死的病因是多因素的,脑内多发性病灶为主要表现,血液高凝状态是血栓形成的可能发生机制,治疗应强调多因素、个体化。
Objective To evaluate the clinical characteristics,neuroimaging characteristics and its treatment of patients with non-nervous system malignancy related acute ischemic stroke.Methods Data were collected retrospectively from50 patients with non-nervous system malignancy related acute ischemic stroke who treated in author＇s hospital between May 2013 and May 2015.The patients were analysed including clinical manifestation and neuroimaging.Results Univariate prognostic analysis showed that hypertension was predictor of non-nervous system malignancy related acute ischemic stroke.Multivariate prognostic analysis showed hemoglobin,blood platelets count,blood clots binomial（fibrinogen,D-dimer）,cerebral infraction lesions were related the predictors.Conclusions The etiology of patients with non-nervous system malignancy related acute ischemic stroke can be multiple factor.The intracerebral multiple lesions were main expression.The hypercoagulable state is a possible mechanism of thrombosis.The treatment of these patients should be biased in favor of multiple factors and individual.
出处
《中国煤炭工业医学杂志》
2016年第9期1265-1269,共5页
Chinese Journal of Coal Industry Medicine
基金
河北省卫生厅科研项目(编号:20120460)
