期刊文献+

促性腺激素释放激素类似物对卵巢肿瘤化疗患者卵巢功能的保护作用 被引量:6

下载PDF
导出
摘要 卵巢肿瘤已成为严重威胁妇女生命和健康的主要疾病,虽然化疗药物的应用使得各种肿瘤治愈率得到提高,但其所带来的并发症也令众多临床医师不可小觑。其中,以卵巢生殖细胞肿瘤尤甚,青春期前患者可占60%~90%。然而,在女性生殖系统中,卵巢对化疗药物最敏感,长期大剂量的化疗会破坏卵巢组织,引起卵巢功能障碍,使得女性患者出现卵巢早衰(premature overy failure,POF),
出处 《中国药物与临床》 CAS 2016年第9期1300-1302,共3页 Chinese Remedies & Clinics
基金 山西省科技产业化环境建设项目(2014071011)
  • 相关文献

参考文献17

  • 1Longhi A,Pignotti E,Versari M,et al.Effect of oral contraceptive on ovarian function in young females undergoing neoadjuvant chemotherapy treatment for osteosarcoma[J].Oncology Reports,2003,10(1):151-155.
  • 2Kitajima Y,Endo T,Nagasawa K,et al.Hyperstimulation and a gonadotropin-releasing hormone agonist modulate ovarian vascular permeability by altering expression of the tight junction protein claudin-5[J].Endocrinology,2006,147(2):694-699.
  • 3Blumenfeld Z.How to preserve fertility in young women exposed to chemotherapy:the role of Gn RH agonist cotreatment in addition to cryopreservation of embrya,oocytes,or ovaries[J].Oncologist,2007,12(9):1044.
  • 4Gunthert AR,Grundker C,Hollmann K,et al.Luteinizing hormone-releasing hormone induces Jun D-DNA binding and extends cell cycle in human ovarian cancer cells[J].Biochem Biophys Res Commun,2002,294:11-15.
  • 5李欢,辛晓燕,黄艳红,赵雪静.曲普瑞林对化疗药物引起卵巢损伤的预防作用[J].中国妇幼保健,2008,23(25):3580-3582. 被引量:3
  • 6Huser M,Zakova J,Smardova L,et al.Combination of fertility preservation strategies in young women with recently diagnosed cancer[J].Eur J Gynaecol Oncol,2012,33(1):42.
  • 7孙玮,傅士龙,韩素萍.卵巢恶性生殖细胞肿瘤的治疗进展[J].现代妇产科进展,2012,21(4):313-315. 被引量:5
  • 8吴夏筠,黄宏伟,董小萍,宋婵吴.戈舍瑞林对卵巢恶性肿瘤化疗后卵巢功能的保护[J].现代医院,2015,15(5):53-54. 被引量:5
  • 9贾国丛,赵晓燕,任胜楠.戈舍瑞林对绝经前乳腺癌患者化疗期间卵巢功能的保护[J].中国普通外科杂志,2011,20(11):1188-1191. 被引量:6
  • 10Abdel-Hady ES,Abdel-Hady HR,Gamal A,et al.Fertility sparing surgery for ovarian tumors in children and young adults[J].Arch Gynecol Obstet,2012,285(2):469-471.

二级参考文献83

  • 1张志强,江泽飞,宋三泰,王涛,申戈,于静新,张少华,闫敏.诺雷德联合瑞宁得治疗绝经前复发转移性乳腺癌的临床研究[J].癌症进展,2004,2(2):127-130. 被引量:17
  • 2郄明蓉,侯敏敏,曹泽毅,张崇淑,彭芝兰,王红静,郑艾.卵巢恶性肿瘤年轻患者保留生育功能手术的效果评价[J].中华妇产科杂志,2006,41(4):233-236. 被引量:15
  • 3艾浩,牛建昭,薛晓鸥,王继峰,李健,李彧.化疗损伤性卵巢功能早衰小鼠动物模型的研究[J].中国实验动物学报,2007,15(1):35-38. 被引量:30
  • 4Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2006 [J]. CA Cancer J Clin, 2006, 56(2) :106- 130.
  • 5Pereyra Pacheco B, M6ndez Ribas JM, Mi|one G, et al. Use of GnRH analogs for functional protection of the ovary and preservation of fertility during cancer treatment in adoles- cents: a preliminary report [ J]. Gynecol Oneol, 2001, 81 (3) :391 -397.
  • 6Recchia F, Saggio G, Amiconi G, et al. Gonadotropin-releasing hormone analogues added to adjuvant chemotherapy protect ovarian function and improve clinical outcomes in young women with early breast carcinoma [ J ]. Cancer, 2006, 106(3) :514 -523.
  • 7Baum M, Hackshaw A, Houghton J, et al. Adjuvant gose- relin in pre-mcnopausal patients with early breast cancer: Results fl'om the ZIPP study [ J ] . Eur J Cancer, 2006 , 42(7) :895 -904.
  • 8Goel S, Sharma R, Hamilton A, et al. LHRH agonists for adjuvant therapy of early breast cancer in premenopausal women[J]. Cochrane Database Syst Rev, 2009, (4) : CD004562.
  • 9Hackshaw A, Baum M , Fornander T, et al. Long-term effectiveness of adjuvant goserelin in premenopausal women with early breast cancer[ J]. J Nat1 Cancer lnst, 2009, 101 (5) :341 -349.
  • 10Sakurai K, Enomoto K, Amano S, et al. Recovery of menstruation after long-term chemotherapy and endocrine therapy in pre-menopausal patients with breast cancer [ J ] . J Cancer Res Clin Oncol, 2011 , 137(4) :615 -620.

共引文献38

同被引文献66

引证文献6

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部