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胃酸与功能性消化不良 被引量：12

Gastric acid and functional dyspepsia
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摘要 功能性消化不良(functional dyspepsia,FD)发病机制尚不完全清楚,胃酸分泌异常是参与FD发病的重要环节。抑酸是治疗FD的常用手段,但胃酸与FD之间的关系尚不完全清楚,FD的抑酸治疗也存在诸多争议。 The pathogenesis of functional dyspepsia （FD） is not entirely clear, abnormal gastric acid secretion is an important part of the onset of this disease. Acid suppression is a common method for the treatment of FD. However, the relationship between gastric acid and FD is not clear, so the method of acid suppression is controversial.
作者 邓葵 刘纯伦
机构地区 重庆医科大学附属第一医院消化科
出处 《胃肠病学和肝病学杂志》 CAS 2016年第9期1058-1061,共4页 Chinese Journal of Gastroenterology and Hepatology
关键词 功能性消化不良 胃酸 抑酸治疗 Functional dyspepsia Gastric acid Acid suppression treatment
分类号 R573.9 [医药卫生—消化系统]
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参考文献28

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  • 2Oshima T, Okugawa T, Tomita T, et al. Generation of dyspeptic symp-toms by direct acid and water infusion into the stomachs of functionaldyspepsia patients and healthy subjects [ J] . Aliment Pharmacol Ther,2012, 35(1 ) : 175-182.
  • 3Lee KJ, Kim JH, Cho SW. Dyspeptic symptoms associated with hyper-sensitivity to gastric distension induced by duodenal acidification [J].J Gastroenterol Hepatol, 2006,21 (3) : 515-520.
  • 4Farre R , Vanheel H , Yanuytsel T, et al. In functional dyspepsia, hy-persensitivity to postprandial distention correlates with meal-relatedsymptom severity [J]. Gastroenterology, 2013 , 145(3): 566-573.
  • 5Ishii M , Kusunoki H , Manabe N , et al. Evaluation of duodenal hypersen-sitivity induced by duodenal acidification using transnasal endoscopy [ J].J Gastroenterol Hepatol, 2010 , 25(5) : 913-918.
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胃肠病学和肝病学杂志
2016年 第9期

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