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门冬氨酸鸟氨酸预防肝硬化上消化道出血诱发肝性脑病的疗效观察 被引量:4

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摘要 目的观察门冬氨酸鸟氨酸预防肝硬化患者上消化道出血诱发肝性脑病(HE)的疗效。方法收集肝硬化导致的上消化道出血患者60例,随机分为治疗组和对照组。对照组给予常规内科护肝对症综合治疗;治疗组在综合治疗基础上加用门冬氨酸鸟氨酸;1周后观察各组临床症状、数字连接试验(Nc T)、肝功能及血氨等变化,比较各组疗效。结果治疗组4例(13.3%)、对照组17例(56.6%)发生HE,二组比较差异均有统计学意义(P均<0.05)。治疗组在肝功能改善、预防血氨上升及Nc T延长方面均有明显作用(P均<0.05),结论门冬氨酸鸟氨酸能有效预防肝硬化患者消化道出血诱发HE。
出处 《中国医药指南》 2016年第24期149-150,共2页 Guide of China Medicine
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