儿童郎格汉组织细胞增生症的肺部HRCT表现

Pulmonary HRCT Manifestations of Langerhans Cell Histiocytosis in Children

目的研究儿童郎格汉组织细胞增生症的肺部HRCT表现。方法选取2010年1月-2016年1月收入我院并确诊的儿童郎格汉组织细胞增生症且肺部HRCT资料完整的儿童患者23例为研究对象,分析其HRCT图像。结果单发或多发结节2例;磨玻璃密度影9例;间隔增厚、胸膜增厚10例;小泡状透亮影4例,其中3例磨玻璃密度影及1例小泡状透亮影合并小叶间隔、胸膜增厚。所有患者HRCT图像均未显示肺门纵隔淋巴结肿大。结论儿童郎格汉组织细胞增生症肺部HRCT表现包括单发或多发结节、磨玻璃密度影、间隔、胸膜增厚、小泡状透亮影等,HRCT可清晰显示患者肺部改变及转归。

Objective To investigate the pulmonary HRCT manifestations of Langerhans cell histiocytosis in children.Methods 23 Langerhans cell histiocytosis patients were selected and 16 slice spiral CT was used to observe the pulmonary situation.Results 2 cases were single or multiple nodules, 9 cases were grinding of glass density. 10 cases were septal thickening and pleural thickening： adjacent to the pleural or leaf thickness, no clear edge; 4 cases were alveolus lucency shadow. Of which 3 cases of ground glass opacity and 1 cases of alveolar interval, pleural thickening with radiolucent shadow.Conclusion Children with Lang Gehan organization cell hyperplasia disease showed lung HRCT manifestations including single or multiple nodules and ground glass opacity, spacing, pleural thickening, alveolar radiolucent shadow without hilar and mediastinal lymph node enlargement, and can clearly display symptoms.