小剂量阿司匹林和低分子肝素在子痫前期防治中的应用概况

The application of a small dose of aspirin and low molecular weight heparin in the prevention and treatment of preeclampsia

子痫前期是妊娠期特有疾病之一。研究表明,妊娠期凝血功能的改变是子痫前期发病机制中的一个重要环节,合理应用抗凝治疗可以有效预防和治疗该疾病及其并发症。阿司匹林和低分子肝素是目前应用较多的抗凝药物。该文对这两种药物在子痫前期预防和治疗中的应用概况进行综述。

Preeclampsia（PE） is one of the specific diseases during pregnancy. Many researches show that the changes of the blood coagulation function during pregnancy are the main causes of PE, and a reasonable applica- tion of anticoagulant therapy can effectively prevent and treat the disease^and its complications. Low molecular weight heparin and aspirin are the most commonly used anticoagulant drugs. In this paper, the studies on the application of the two drugs in the prevention and treatment of PE are reviewed.