探究女性下生殖道性传播病原体感染与输卵管妊娠及预后的相关性

Relevance between sexually transmitted pathogens infection of female lower genital tract infection and tubal pregnancy

目的：分析女性下生殖道性传播病原体感染与输卵管妊娠的相关性,探讨输卵管妊娠术后采用敏感抗生素治疗的效果。方法：将2013年2月至2015年2月于我院行手术治疗的120例输卵管妊娠患者纳入试验组,同期于我院行人工或药物流产的110例健康妊娠女性纳入对照组,分析性传播病原体阳性率与输卵管妊娠发生的相关性,同时将试验组中有生育需求的CT、UU阳性患者纳入观察组,其余纳入预防组,探讨敏感抗生素治疗对患者预后的影响。结果：试验组的CT、UU和CT＋UU阳性率分别为19.2%、40.8%和9.2%,均高于对照组的4.5%、17.3%和0.9%,差异有显著性意义（χ^2=11.48、15.30、7.91,P〈0.01）;试验组中,2次及以上输卵管妊娠的患者CT、UU和CT＋UU阳性率分别为37.5%、66.7%和25.0%,均高于首次输卵管妊娠患者的16.7%、36.5%和6.3%,差异有显著性意义（χ^2=5.03、7.16、5.51,P〈0.05）;观察组与预防组输卵管通畅率分别为88.2%、74.1%,两组差异相比无显著性意义（χ^2=0.78,P〉0.05）。结论：CT、UU感染与输卵管妊娠的发生有关,采用药敏抗生素治疗患者及其配偶能够有效改善输卵管妊娠患者的预后。

Objectives： To analyze the correlation between sexually transmitted pathogens infection of fe- male reproductive tract and tubal pregnancy （ TP）, to discuss the effect of postoperative sensitive antibiotic treatment. Methods： 120 TP patients in our hospital from February 2013 to February 2015 were selected into the experimental group, while 110 healthy pregnant women conducted artificial or medical abortion were included as the control group, to analyze the correlation between positive rate of sexually transmitted pathogens and TP. CT and UU positive patients with fertility requirements in experimental group were included as observation group while the rest were prevention group, to explore the effect of sensitive antibiotic treatment on the prognosis of patients. Results： The positive rate of CT, UU and CT ＋ UU was 19.2%, 40. 8% and 9.2% respectively, higher than the control group of 4.5%, 17.3% and 0. 9%, with significant difference （χ^2= 11.48, 15.30, 7.91, P〈0.01）. In the experimental group, for patients with twice and more times of TP, the CT, UU and CT ＋ UU were 37.5%, 66.7% and 25.0% respectively, higher than those of patients with once TP which were 16.7%, 36.5% and 6.3% , with significant differences （χ^2 = 5.03, 7.16, 5.51, P 〈 0. 05）. The tubal patency rate of observation and prevention group were 88.2% and 88.2% respectively, without significant difference （ χ^2= 0. 78, P 〉 0. 78）. Conclusion： CT and UU infection is associated with the occurrence of TP, and drug sensitive antibiotics for patients and their spouses can effectively improve the prognosis of patients.