四妙散加味联合左卡尼汀治疗少、弱精症疗效观察

Curative effect of Simiaosan jiawei combined with l-carnitine on asthenozoospermia

目的:观察中药四妙散加味治疗湿热下注证少、弱精症临床疗效。方法:选取符合标准的42例患者,服用四妙散加味和左卡尼汀口服液联合治疗。结果:42例患者治疗后痊愈16例,显效18例,有效4例,无效4例,总有效率为90.48%。治疗4周后自身前后对照精液量、活动率、精子密度、(a+b)级精子含量差异均无统计学意义(P>0.05);治疗8周后差异具有统计学意义(P<0.05);治疗12周后差异具有显著统计学意义(P<0.01)。结论:四妙散加味联合左卡尼汀口服液治疗少、弱精症具有较好临床疗效,值得进一步研究。

Objectives： To observe the clinical curative effect of traditional Chinese medicine （TCM） Simiaosan jiawei in treating asthenozoospermia. Methods： 42 patients meeting the criterion were selected and treated with Simiaosan jiawei combined with 1 - carnitine. Results ： According to the results of 42 patients, there were 16 cured cases after treatment, 18 cases with markedly effect, 4 cases with effective results and 4 invalid cases. The total effective rate was 90. 48%. The differences in semen quantity, activity rate, sperm density, and sperm （grade a ＋ b） content between 4 weeks after treatment and before the treatment had no statistical significance （ P 〉 0. 05 ）. The difference between 8 weeks after treatment and before the treatment was statistically significant （ P 〈 0. 05 ） ; The differences between 12 weeks after treatment and before the treatment had statistical significance （P 〈 0. 01 ）. Conclusion ： Simiaosan jiawei combined with 1 - carnitine has good clinical curative effect in the treatment of asthe- nozoospermia, which is worthy of further investigation.