摘要
目的:探讨妊娠期泌尿生殖系统、肠道、皮肤、口腔感染的相互关系。方法:通过问卷调查、临床诊断、尿液和粪便样本检查研究262例孕妇的感染情况。利用多元回归分析不同病原体感染之间的相互作用。结果:孕妇在各种感染下的患病率分别为:阴道炎90.2%,阴道滴虫病76.0%,细菌性阴道炎63.0%,钩虫58.0%,无症状菌尿或尿路感染61.5%,宫颈炎30.5%;阴道酵母菌(21.0%),阴道双球菌(17.9%),蛔虫(34.0%),鞭虫(11.8%);龋齿(19.1%),疥疮(17.2%)。多重回归分析显示在妊娠期滴虫病和AB/UTI、双球菌和蛔虫之间呈现正相关,而BV和滴虫病、钩虫和双球菌之间则呈现着负相关。妊娠期间阴道乳酸菌数量的增多减少了双球菌出现的几率,但是增加了蛔虫卵感染度和滴虫病出现的几率。结论:当我们只针对一种感染治疗的时候可能增加其它病原体感染的风险,因此当临床治疗时需注意这些感染的正、负相关性,以确保一个合适的方案来治疗与管理合并感染。
Objectives: To explore the interrelationships among urogenital, the intestinal tract, skin and oral infection in pregnancy through a cross- sectional survey. Methods: Questionnaire investigation, clinical diagnosis, urine and stool samples were applied to detect the infection of 262 pregnant women. And the relationship between different pathogen infections was examined by the multiple regression analysis. Results: The prevalence of pregnancy of different infections were : vaginitis (90. 2 % ) , vaginal trichomoniasis (76.0 % ) , bacterial vaginosis (BV; 63.0 % ), hookworm (58.0 % ), asymptomatie bacteriuria/urinary tract infection (AB/UTI; 61.5 % , cervicitis (30.5 %), vaginal yeast 21. 0 %), Ascaris (34. 0 %), vaginal diplococci (17.9 %), caries ( 19. 1% ) , scabies ( 17.2 % ) , and Trichuris ( 11.8 % ). Multiple regression analysis revealed positive associations (trichomoniasis and AB/UTI or diplococcus and Ascaris) and negative associations (BV and trichomoniasis; hookworm and diplococci) during pregnancy. Vaginal lactobacillus reduced chances of getting diplococeus, but increased Ascaris eggs per gram (epg) and trichomoniasis infection in pregnancy. Conclusion: Treatment against one kind of infection may increase the risk of others. Therefore, attention should be paid to the positive and negative correlation between these infections, to ensure a proper solution for combined infection.
出处
《中国性科学》
2016年第9期116-120,共5页
Chinese Journal of Human Sexuality
关键词
妊娠期
细菌感染
真菌感染
原生动物感染
寄生虫
Pregnancy
Bacterial infections
Fungal infection
Protozoa infections
Parasites