轻中度痤疮患者痤疮部位与正常部位皮肤生理参数的差异

Differences of physiological indicators between healthy normal skin and acne site of mild and moderateacne patients

目的研究轻中度痤疮患者痤疮部位与健康正常皮肤部位生理指标的差异。方法选取75例痤疮患者检测痤疮部位皮脂分泌量、表皮含水量、皮肤p H值。另外检测63例轻中度痤疮患者痤疮部位与痤疮周围10 cm健康皮肤部位的皮脂分泌量、表皮含水量、皮肤p H值。结果根据每个痤疮患者痤疮部位皮脂分泌量增多、表皮含水量减少的程度不同,可分为轻中重度痤疮;轻中度痤疮患者痤疮部位与健康皮肤比较,痤疮部位皮脂分泌量显著高于周围健康皮肤(t=2.786,P=0.006<0.05),表皮角质层含水量明显低于皮肤健康部位(t=2.648,P=0.009<0.05),痤疮部位皮肤p H值与健康皮肤相比减小(t=3.028,P=0.003<0.05)。结论轻中度痤疮患者痤疮部位与其周围10 cm健康部位比较,皮脂分泌量显著增多、表皮含水量明显降低、皮肤p H值下降。

Objective To investigate the differences of physiological indicators between healthy normal skin and acne site of mild and moderate acne patients. Methods The 75 acne patients were enrolled in this study. Sebum secretion, moisture of skin, and skin PH value in acne site and the surrounding 10cm healthy skin of the 63 mild and moderate acne patients were tested. Results According to the different degree of an increase of sebum secretion, a reduction of skin moisture content in acne site of each acne patient, the acne were divided into the mild, moderate and severe acne. Sebum secretion of the mild and moderate acne was significantly higher than the healthy skin （ t=2.786,P=0.006,P〈0.05） , moisture of skin was lower than the control （ t=2.648,P=0.009,P〈0.05）, skin PH value was decreased （t=3.028,P=0.003,P〈0.05）. Conclusions Compared the acne site with the surrounding 10cm healthy skin of the mild and moderate acne, we find the amount of sebum secretion increased significantly, the skin moisture content decreased, the skin pH value decreased.