育龄妇女泌尿生殖道无乳链球菌感染情况与耐药性分析

Urogenital tract infection by Streptococcus agalactiae and the drug resistance among women of child-bearing age

目的探讨育龄妇女泌尿生殖道无乳链球菌感染情况与耐药性。方法选择3 000例在我院就诊的育龄期妇女,所有患者送检泌尿道或生殖道标本,进行无乳链球菌培养及药物敏感性试验,探讨育龄妇女泌尿生殖道无乳链球菌感染情况及耐药性。结果 3 000例育龄妇女中177例感染无乳链球菌,感染率5.90%,其中肾内科患者感染率最高,达到8.97%。2012至2015年育龄期妇女无乳链球菌感染率逐年增加。无乳链球菌对四环素、克林霉素、红霉素、左氧氟沙星耐药性较高,分别达到80.80%、60.45%、56.50%、45.20%。无乳链球菌对头孢曲松、头孢他啶、亚胺培南、万古霉素未产生耐药性。结论育龄妇女无乳链球菌感染率较高,呈逐年上升趋势,防治形势严峻,无乳链球菌对多种常用抗生素耐药率较高,应根据药敏结果合理使用抗生素。

Objective To discuss the urogenital tract infection by and the drug resistance of Streptococcus agalactiae among women of child-bearing age.Methods 3,000 women of child-bearing age accepting medical treatment in our hospital were selected,whose urinary tract or genital tract samples were detected for Streptococcus agalactiae and drug sensitivity.The Streptococcus agalactiae infection of urogenital tract and drug resistance were analyzed.Results 177 cases were Streptococcus agalactiae positive with an infection rate of 5.90%;the top infection rate was seen in Department of Urology,reaching up to 8.97%.The infection rate rose year by year from 2012 to 2015.The drug resistance rates of Streptococcus agalactiae was80.80%to tetracycline,60.45% to clindamycin,56.50% to erythromycin,and 45.20% to levofloxacin.No strains appeared to be resistant to ceftriaxone,ceftazidime,imipenem and vancomycin.Conclusion The rate of Streptococcus agalactiae infection is high among women of child-bearing age,which rises year by year,representing a challenge to the prevention and control of the infection.The drug resistance of Streptococcus agalactiae to many common antibiotics are high.Antibiotics should be used reasonably according to the results of drug sensitivity test.