液氮冷冻治疗带状疱疹合并抗-HIV阳性患者临床观察

Clinical observation of liquid nitrogen cryotherapy in the treatment of patients with herpes zoster and positive anti-HIV

目的:观察液氮冷冻治疗带状疱疹合并抗-HIV阳性患者的临床疗效.方法:选取四川省凉山彝族自治州第二人民医院2012-03/2015-12收治的带状疱疹合并抗-HIV阳性患者50例作为研究对象,将其随机分为冷冻组(n=24)和对照组(n=26),两组均予抗病毒、止痛、营养神经基础治疗,冷冻组同时给予液氮冷冻治疗,分别于治疗第7日、14日对两组患者进行疗效评估.结果:冷冻组与对照组第7日综合疗效比较,差异无统计学意义(P>0.05),冷冻组第14日综合疗效优于对照组,差异具有统计学意义(P<0.05).结论:液氮冷冻治疗带状疱疹合并抗-HIV阳性患者疗效肯定,值得应用推广.

AIM： To observe the curative effect of liquid nitro- gen cryotherapy in the treatment of patients with herpes zoster and positive anti-HIV. METHODS ： A total of 50 patients with herpes zoster and positive anti-HIV admitted into The Second People＇s Hospital of Liangshan Yi Autonomous Prefecture from March 2012 to December 2015 were selected as objects of study and randomly divided into freezing group （ n = 24） and control group （ n = 26 ）, both of which received basic treatment such as antiviral, analge- sic, and neurotrophic treatments. The freezing group also received liquid nitrogen cryotherapy. The curative effect was evaluated on 7 and 14 days after the treatment respectively. RESULTS： For the comprehensive therapeutic effect on 7 days after the treatment, there was no statistically significant difference between the freez- ing group and control group （P〉0.05）. While the comprehensive therapeutic effect in freezing group on 14 days after the treatment was better than the control group, and the difference was statisti- cally significant （ P 〈 0.05 ）. CONCLUSION： Liquid nitrogen cryotherapy is an effective method for treating herpes zoster with positive anti-HIV patients, which is worthy of application and popularization.