急危重症脑卒中患者接受不同营养支持治疗对脏器功能的影响分析

Effects of Different Nutrition Support Treatment on Organ Function in Patients with Acute Critical Care Stroke

目的探讨急性重症脑卒中患者接受不同营养支持治疗对脏器功能的影响。方法选择100例急危重症脑卒中患者,随机分为A组和B组,A组患者接受肠内营养治疗,B组患者接受肠外营养治疗,每组50例,进行对照观察,观察期间记录两组患者不同时刻的脏器功能(ALT、SCr、CPIS、GCS)。结果和治疗前相比,A组ALT随着治疗时间逐渐升高,B组患者由于肝功能损伤严重,治疗后5天急剧升高,治疗后第14天减缓;A组SCr随着治疗时间逐渐下降,B组下降不明显;两组患者CPIS均先升高后下降,而A组下降幅度更大;两组GCS均逐渐升高,但A组上升幅度较B组更大。以上四个指标在组间、不同时刻相比较均有显著差异(P<0.05)。结论早期肠内营养支持较肠外营养支持更能改善危重症脑卒中患者脏器功能,进而降低多脏器功能障碍综合征的发生风险。

Objective To investigate the severe acute cerebral apoplexy patients accepted the influence of different nutrition support therapy on the viscera fimctiou. Methods 100 cases of acute severe cerebral apoplexy patients were randomly divided into group A and group B. Group A patients received enteral nutrition therapy, and group B patients received parenteral nutrition therapy, 50 cases in each group. The viscera function index （ ALT, SCr, CPIS, GCS ） of the two groups of patients in different time were compared. Results Compared with before treatment, ALT of group A was increased with treatment time. B group because ofsevei＇e liver function damage, ALT dramatic increased in 5 days after treatment, and the 14th day decreased; SCr of group A was decreased with the treatment time, and group B decline was not obvious; CPIS of two groups was increased firstly and then decreased, and group A dropped more; GCS of two groups were increased, and group A rose more. The above four index compared between groups, different time had significant difference （ P 〈 0.05 ） . Conclusion Early enteral nutrition support than parenteral nutrition support can improve more critically ill viscera fimction in patients with cerebral apoplexy, and reduce the risk ofnmltiple organ dysfunction syndrome.