脱水剂与阿糖腺苷联合治疗小儿病毒性脑炎的疗效分析

The Effect of Dehydration Combined with Vidarabine Monophosphate in Children with Viral Encephalitis

目的探讨脱水剂与阿糖腺苷联合治疗小儿病毒性脑炎的疗效。方法选取我院收治的72例病毒性脑炎患儿,分为对照组和研究组,每组36例,对照组患者采用单磷酸阿糖腺苷治疗,研究组在对照组的基础上联合给予脱水剂甘露醇治疗,对比两组患者的临床治疗效果。结果研究组治疗总有效率为91.67%,对照组治疗总有效率为77.78%,两组比较差异有统计学意义(P<0.05),治疗后研究组患者的退热时间、意识恢复时间、惊厥控制时间以及头痛呕吐消失时间少于对照组(P<0.05)。结论脱水剂与阿糖腺苷联合治疗小儿病毒性脑炎能有效的改善患儿的临床症状,疗效显著。

Objective To investigate the clinical effect of dehydration combined with vidarabine monophosphate in children with viral encephalitis. Methods 72 cases children with viral encephalitis in our hospital were divided into observation group （ n=36 ） anti control group （ n=36 ） according to the therapeutic methods. Children in the control group were treated with vidarabine monophosphate, and children in the observation group were treated with dehydration combined with vidarabine monophosphate. The clinical effect were compared between the two groups. Results The clinical efficacy rate of the observation group （ 91.67% ） was significantly higher than that of the control group （ 77.78% ） （ P - 0.05 ） . After treatment, the antifebrile time, consciousness recovery time, convulsions control time and headaches, vomiting disappear time of the observation group were significantly less than those of the control group （P〈 0.05 ） . Conclusion Dehydration combined with vidarabine monophosphate in children with viral encephalitis could effectively improve the children＇s clinical symptoms and has remarkable clinical effect.