尼群地平联合厄贝沙坦用于老年性高血压疗效观察

Observation of Curative Effect of Nitrendipine Combined with Irbesartan for Senile Hypertension

目的 探讨尼群地平联合厄贝沙坦对老年性高血压患者进行治疗的临床疗效及安全性。方法 收集自2014年9月-2016年2月在我院接受治疗的204例老年性高血压患者的临床资料进行分析,按照随机分配原则把老年性高血压患者分成对照组和观察组各102例。对照组采用尼群地平治疗;观察组采用尼群地平＋厄贝沙坦治疗。观察比较治疗的患者的临床疗效。结果 观察组患者的总有效率为93.1%、显效率为71.6%、无效率为6.9%,均优于对照组的82.4%、49.0%和17.6%,差异有统计学意义（P〈0.05）。结论 采用尼群地平联合厄贝沙坦对老年性高血压患者进行治疗具有较好的临床效果。

Objective To investigate treatment efficacy and safety of the nitrendipine combined with irbesartan in senile hyl-ertension. Methods The clinical data 204 cases of senile hypertensive from September 2014 to February 2016 in our hospital were analyzed, and all cases were divided into control group and observation group randomly, each group of 102 cases . Control group was treated wiht nitrendipine; Observation group was treated with nitrendipine combined with irbesartan. The climeal efficacy of two groups were compared. Result8 Total effective rate oft.he observation group was 93.1%, effective rate was 71.6%, and invalid rate was 6.9%, which were better than the control group （ 82.4%, 49.0% and 17.6% ）, and the difference was significant （ P 〈 0.05 ） . Conclusion Nitrendipme combined with irbesartan for senile hypertension shows better clinical efficacy.