苄星青霉素对早期梅毒的治疗效果观察

Analysis of the Curative Effect of Benzathine Benzylpenicillin in Patients with Early Syphilis

目的分析苄星青霉素对早期梅毒的治疗效果。方法按照就诊顺序将我科收治的60例早期梅毒患者分为观察组及对照组,各30例,分别应用苄星青霉素及阿奇霉素,比较两组临床疗效。结果观察组皮疹消失时间显著短于对照组(P<0.05)。观察组3个月、6个月、12个月治愈率分别为30.00%、70.00%、96.67%,均显著高于对照组6.67%、43.33%、73.33%(P<0.05)。结论应用苄星青霉素治疗早期梅毒可有效杀灭梅毒螺旋体,改善临床症状,疗效显著。

Objective To analyze the effect of benzathine benzylpenicillin in patients with early syphilis. Methods 60 cases of patients with early syphilis were randomly divided into the observation group and the control group, 30 cases in each group. They were respectively applied benzathine penicillin and azithromycin. The clinical efficacy of two groups were compared. Results The symptoms disappear time of the observation group was significantly shorter than the control group （P 〈 0.05 ） . Treatment for 3 months, 6 months, 12 months, the serum cure rate of the observation group respectively were 30.00%, 70.00%, 96.67%, which were significantly higher than that of control group 6.67%, 43.33%, 73.33% （P 〈 0.05 ） . Conclusion Application of benzathine penicillin in the treatment of early syphilis can effectively kill treponema paUidum, improve clinical symptoms.