摘要
目的 研究慢性阻塞性肺疾病患者1,25-二羟维生素D3及血清钙水平及肺功能相关性。方法 选取我院2014年9月-2016年3月入院治疗的慢性阻塞性肺疾病患者和正常体检者共80例作为研究对象,分别作为实验组和对照组,实验组为慢性阻塞性肺疾病患者50例,对照组为正常体检者30例。对研究对象的血清1,25（OH）2D3、血清钙水平及肺功能进行检测和测量,比较分析两组间的数据差异。结果 实验组血清1,25（OH）2D3及血清钙值均低于对照组（P〈0.05）。根据病情的轻重程度进行分析后,轻度的实验组患者血清1,25（OH）2D3及血清钙值与对照组无统计学意义（P〉0.05）。而中度到极重度的患者血清1,25（OH）2D3及血清钙值均低于对照组（P〈0.05）。且慢性阻塞性肺疾病患者的血清1,25（OH）2D3及血清钙值随病情严重程度增高而递减。结论 慢性阻塞性肺疾病患者的血清1,25（OH）2D3、血清钙水平大多低于健康者,其水平的高低因病情的轻重而变化。
Objective To study the correlation of Chronic obstructive pulmonary disease patients 1, 25-dihydroxyvitamin D3 and serum calcium levels and pulmonary function. Methods Patients with chronic obstructive and normal physical examination from September 2014 to March 2016 hospitalized were selected, a total of 80 cases as the research objects, they were considered as the experimental group and control group, experimental group of St） patients with chronic obstructive, the control group of 30 cases of normal physical examination. The patient＇s serum 1, 25 （ OH ） 2D3, serum calcium levels and hmg fimction was measured, the data of two groups was comparative analyzed. Results The serum 1, 25 （ OH ） 2D3 and serum calcium value of the experimental group were lower than the control group （ P 〈 0.05 ） . According to the weight of the illness degree analysis, a mild form of the experimental group patients serum level compared with the control group with no statistical significance （ P 〉 0.05 ） . And moderate to very severe patients serum levels were lower than control group （ P〈 0.05 ） . And chronic obstructive pulmonary disease patients serum 1, 25 （ OH ） 2D3 and serum calcium valne decreased with the illness severity increases. Conclusion Chronic obstructive pulnmnary disease in patients with serum 1, 25 （ OH ） 2D3, serum calcium levels is lower than the healthy subjects mostly, its level of high and low change due to the weight of the illness.
出处
《中国卫生标准管理》
2016年第16期156-157,共2页
China Health Standard Management
