贵州省农村地区病毒性脑炎感染现状研究

The Studies of Viral Encephalitis Infection in Guizhou's Rural Areas

目的了解贵州省农村地区病毒性脑炎的发病现状。方法收集2007年德江、榕江2个国家级乙脑监测县报告的75例急性病毒性脑炎病例的资料,其中71例进行乙脑病毒及其它10种病毒性脑炎病毒感染的血清学、病原学和/或分子生物学检测,31例配合随访调查。结果2个县的急性病毒性脑炎发病率为9.3/10万,死亡率为6.5%,后遗症发生率为45.2%。乙脑病毒感染率50.7%(36/71),肠道病毒等乙脑以外病毒性脑炎病毒感染率26.8%(19/71)。结论贵州省农村地区病毒性脑炎的发病形势较严峻;以乙脑病毒感染为主,应加强乙脑和非乙脑病毒性脑炎的监测、控制和研究。

Objective To explore the current situation of viral encephalitis in Guizhou＇s rural areas. MethodsThe medical records of 75 case s of acute viral encephalitis（AVE）were selected from Dejiang county and Rongjiang county. The serology,etiology and molecular biology of encephalitis virus and other 10 kinds of viral encephalitis virus in 71 casess were detected. 31 cases with follow-up survey.ResultsThe AVE incidence of this two county was 9.3/100 000,and the mortality rate was 6.5%,the incidence rate of clinical sequelae was 45.2%. The infection rate of encephalitis virus was 50.7%（36/71）. The infection rate of intestinal virus and other virus was 26.8%（19/71）.ConclusionDisease situation of viral encephalitis infection in Guizhou＇s rural areas is more serious,and the monitoring,control,and research of viral encephalitis shoud be strengthen.