应用组织多普勒速度成像技术研究骨质疏松症患者的心室功能

Research About Ventricular Function in Patients With Osteoporosis by Using Tissue Doppler Imaging

目的应用组织多普勒成像技术(TDI)研究骨质疏松症(OP)患者心室功能的临床价值。方法我院老年病科的OP患者120例为骨质疏松组,以性别及年龄匹配的健康体检者120例为正常对照组(NC),应用TDI技术测量心室功能。结果收缩期:左室侧壁及间隔侧二尖瓣环两个瓣环位点的Sm、S-VTI值在OP组均低于NC组,差异有统计学意义(P均<0.01)。舒张期:左室侧壁二尖瓣环、间隔侧二尖瓣环及右室游离缘三尖瓣环3个瓣环位点的e、e-VTI、e/a值在OP组均低于NC组,差异亦有统计学意义(P<0.01)。结论 OP早期即同时存在左右心室收缩及舒张功能异常,可作为判断OP患者心肌损害严重程度的客观敏感指标。

Objective To research the clinical value of Tissue Doppler Imaging（TDI）technology in assessment of ventricular function in patients with Osteoporosis（OP）.Methods 120 cases of OP patients as positive group,120 cases of healthy volunteers matching with gender and age as normal control（NC）. TDI measurement was taken at lateral and septal mitral annulus as wel as tricuspid annulus in the apical 4-chanber view,to record contraction S-ware peak（Sm）,early diastolic e-ware（e）,late diastolic a-ware peak（a）,velocity time integral of S-ware and E-ware（S-VTI and E-VTI）,e/a ratio,s-ware peak time（Ts-m）,e-ware peak time （Te-m）. ResultsThe Sm and S-VTI at lateral and septal mitral annulus of OP group were lower than that of NC group.E,E-VTI,e/a ratio at three annulus sites of OP group were al significantly lower than that of NC group （P〈0.01）.Conclusion Abnormal of ventricular function exist in the early stage of OP. This sensitive index is used for judging the order of severity of cardiac damage in patients with OP.