二磷酸果糖在小儿先天性心脏病合并心力衰竭中的临床应用观察

Clinical Application of Fructose Diphosphate in Children with Congenital Heart Disease Complicated with Heart Failure

目的 探析二磷酸果糖在治疗小儿先天性心脏病合并心力衰竭中的临床实效。方法 选取本院2013年12月~2015年12月所收治的90例先天性心脏病合并心力衰竭的患儿为本次研究对象,以随机法将其分为对照组及观察组,给予41例对照组患儿以常规治疗,观察组49例患儿则在其基础上以口服的方式施以二磷酸果糖治疗,对两组患儿的临床治疗、不良反应等进行比较。结果 在治疗有效率上,观察组明显高于对照组,在不良反应发生率上,观察组则低于对照组,其差异具有统计学意义（P〈0.05）。结论 二磷酸果糖可显著提升先天性心脏病合并心力衰竭患儿的临床治疗效果,减少并发症的发生率。

Objective To analyze the clinical efficacy of fructose diphosphate in treating children with congenital heart disease complicated with heart failure.MethodsSelected 90 cases in this hospital from December 2013 to December 2015 by admitted of congenital heart merged congestive heart failure of children for this times research object, were randomly divided into control group and the observation group. 41 cases of control group received general treatment, and observation group 49 cases children received fructose diphosphate treatment based on treatment of control group. Clinical efficacy and complications of two groups was compared.Results Efifciency in observation group was signiifcantly higher than the control group, adverse reactions of observation group was lower than the control group, and the difference was statistically significant （P〈0.05）.Conclusion Fructose diphosphate can signiifcantly enhance the therapeutic effect in children with congenital heart disease complicated with heart failure, reducing the incidence of complications.