奥卡西平治疗小儿癫痫部分发作疗效及安全性探讨

Efficacy and Safety of Oxcarbazepine in Treatment of Children with Partial Seizures to Evaluate

目的 研究分析小儿癫痫使用奥卡西平治疗的效果和安全性。方法 根据2010年12月~2015年1月我院的114例癫痫患儿来进行研究分析,将这些患儿分成对照组和观察组,对照组使用丙戊酸钠缓释片治疗,观察组使用奥卡西平治疗,对两组的临床治疗效果和不良反应情况进行对比分析。结果 经过治疗后,观察组的临床有效率是94.7%,不良反应发生率是3.5%,对照组患者的治疗有效率是71.9%,不良反应发生率是10.5%,两组结果对比存在统计学差异性（P〈0.05）。结论 小儿癫痫患者接受奥卡西平治疗的效果突出,安全性比较高,临床中可以广泛使用,改善患儿的病情,提升生活质量。

Objective To analyze the efifcacy and safety of oxcarbazepine in the treatment of children with epilepsy.Methods114 cases of children with epilepsy in our hospital from December 2010 to January 2015 were selected for study, these children were divided into control group and observation group, the control group used sodium valproate sustained release tablets in the treatment, the observation group used oxcarbazepine treatment, two groups of clinical curative effect and adverse reactions was comparative analyzed.Results After treatment, the clinical efficacy rate in the observation group was 94.7%, the adverse reaction rate was 3.5%, the effective rate in the control group was 71.9%, the adverse reaction rate was 10.5%. The result of two groups compared exist significant difference （P〈0.05）.ConclusionChildren with epilepsy patients accepted oxcarbazepine treatment effect is prominent, the security is relatively high, clinical can be widely used, improve the patient＆#39;s condition, improve quality of life.