乳腺癌内乳淋巴结转移根治的相关性研究

Research of correlation between internal mammary node metastasis and radical treatment in breast cancer

目的探讨内乳淋巴结活检相应的改良根治术对乳腺癌患者生存情况的影响。方法 158例位于内侧象限及乳晕周围乳腺癌患者,84例未行内乳前哨淋巴结活检,74例行内乳前哨淋巴结活检,观察病理分级的改变及对乳腺癌转移的影响。结果 74例行内乳前哨淋巴结活检的患者中,取出前哨淋巴结共5例出现了内乳淋巴结对病理分级的改变。未行内乳前哨淋巴结活检的患者肺转移及锁骨上淋巴结转移发生率22.6%、26.2%高于行内乳前哨淋巴结活检的患者10.8%、13.5%(P<0.05)。结论行内乳淋巴结活检的病例中发生转移明显低于未做内乳淋巴结活检的患者。

Objective To investigate influence by corresponding modified radical mastectomy in sentinel lymph node biopsy on survival condition of breast cancer patients. Methods Among 158 patients with interior quadrant and areola breast cancer, 84 cases received no internal mammary sentinel lymph node biopsy and 74 cases received internal mammary sentinel lymph node biopsy. Change of pathological classification and influence on breast cancer metastasis were observed. Results Among 74 cases receiving internal mammary sentinel lymph node biopsy, 5 cases had changed pathological classification in internal mammary node of removed sentinel lymph node. Incidences of pulmonary metastasis and supraclavicular lymph node metastasis in non-internal mammary sentinel lymph node biopsy cases were 22.6% and 26.2%, which were higher than 10.8% and 13.5% in the cases receiving internal mammary sentinel lymph node biopsy（P〈0.05）. Conclusion Incidence of metastasis is obviously lower in patients receiving internal mammary node biopsy than those receiving no internal mammary node biopsy.