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^(125)I粒子植入治疗前列腺癌术后血清PSA分析

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摘要 目的探讨经直肠超声引导下^(125)I粒子植入治疗前列腺癌患者术后血清前列腺特异抗原(PSA)变化及影响治疗效果的危险因素。方法 70例经直肠超声引导下^(125)I粒子植入治疗的前列腺癌患者,依随访结果分为A组(良性反弹组,32例),B组(生化复发组,12例),C组(疗效稳定组,26例)。比较三组PSA的变化及影响治疗效果的危险因素。结果 A组复查血PSA降至最低值后开始升高时间发生在术后(16.5±1.3)个月,且65.6%(21/32)出现于14~27周;B组复查血PSA降至最低值后开始升高时间发生在术后(29.7±2.2)个月;C组复查血PSA降至最低值时后长期保持稳定。治疗时患者年龄是良性反弹的危险因素(OR=0.802,P=0.0025<0.01)。结论超声引导下^(125)I粒子植入治疗前列腺癌术后监测血PSA变化有助于临床对治疗效果的评估。
出处 《中国实用医药》 2016年第25期207-208,共2页 China Practical Medicine
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  • 1陈明,孙则禹,张古田,陈恕求,李俊龙,彭涛,戴玉田.经会阴^(125)I粒子组织间植入治疗局限性前列腺癌临床研究(附10例报告)[J].现代泌尿外科杂志,2007,12(2):101-103. 被引量:7
  • 2KWOK Y, DIBIASE SJ, AMIN PP, et al. Risk group stratification in patients undergoing permanent ^125I prostate rachytherapy as monotherapy [J]. Int J Radiat Oncol Biol Plays, 2002, 53: 588-594.
  • 3BLASKO JC, GRIMM PD, SYLVESTER JE, et al. Palladium-103 brachytherapy for prostate carcinoma [J]. Int J Radiat Oncol Biol Phys, 2000, 46:839-850.
  • 4RAGDE H, ELGAMAL AA, SNOW PB, et al. Ten year disease free survival after transperineal sonography-guided iodine-125 brachytherapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized, low to high Gleason grade prostate carcinoma [J]. Cancer, 1998, 83: 989-1001.
  • 5AILEEN BC, ANTHONY VD, BRIDGET AN, et ah Patient and treatment factors associated with complications after prostate brachytherapy [J]. J Clin Onco, 2006, 24:5298-5304.
  • 6Jemal A, Siegel R, Xu J, et al. Cancer statistics, 2010. CA Cancer J Clin, 2010, 60: 277-300.
  • 7Heidenreich A, Aus G, BoUa M, et al. EAU guidelines on prostate cancer. Eur Urol, 2008, 53: 68-80.
  • 8Kuban DA, Levy LB, Potters L, et al. Comparison of biochemical failure definitions for permanent prostate brachytherapy. Int J Radiat Oncol Biol Phys, 2006, 65: 1487-1493.
  • 9Whitmore WF Jr, Hilaris B, Grabstald H. Retropubic implantation of iodine 125 in the treatment of prostate cancer. J Urol, 1972, 108 : 918-920.
  • 10Potters L, Klein EA, Kattan MW, et al. Monotherapy for stage Tl -T2 prostate cancer: radical prostatectomy, external beam radiotherapy, or permanent seed implantation. Radiother Oncol, 2004, 71 : 29-33.

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