电针为主治疗肝肾阴虚型类风湿关节炎疗效观察

Therapeutic Observation of Electroacupuncture in Treating Rheumatoid Arthritis Due to Liver-kidney Yin Deficiency

目的观察电针配合口服泽苓关节消肿合剂治疗肝肾阴虚型类风湿关节炎的临床疗效。方法将126例活动期肝肾阴虚型类风湿关节炎患者随机分为治疗组和对照组,每组63例。对照组采用口服甲氨蝶呤片和来氟米特片治疗,治疗组在对照组基础上采用电针配合口服泽苓关节消肿合剂治疗。观察两组治疗前后28个关节疾病活动指数(DAS28)变化情况,并比较两组治疗后美国风湿病学院(ACR)疗效及中医证候疗效。结果治疗组ACR总有效率为87.3%,对照组为65.1%。两组ACR疗效比较,差异具有统计学意义(P<0.01)。治疗组中医证候总有效率为87.3%,对照组为73.0%。两组中医证候疗效比较,差异具有统计学意义(P<0.05)。两组治疗后DAS28比较,差异具有统计学意义(P<0.01)。结论电针配合中医药是一种治疗肝肾阴虚型类风湿关节炎的有效方法,能显著提高患者ACR20和中医临床疗效。

Objective To observe the clinical efficacy of electroacupuncture plus oral administration of Zeling Guanjie Xiaozhong Heji in treating rheumatoid arthritis（RA） due to liver-kidney yin deficiency. Method Totally 126 patients with active RA due to liver-kidney yin deficiency were randomized into a treatment group and a control group, 63 cases in each group. The control group was prescribed with orally taking Methotrexate tablets and Leflunomide tablets, while the treatment group was intervened by electroacupuncture plus oral administration of Zeling Guanjie Xiaozhong Heji in addition to the medications given to the control group. The Disease Activity Score 28（DAS28） was evaluated before and after intervention, and the therapeutic efficacies were compared based on the criteria of the American College of Rheumatoid（ACR） and syndrome of traditional Chinese medicine（TCM）. Result The ACR total effective rate was 87.3% in the treatment group versus 65.1% in the control group, and the difference was statistically significant（P〈0.01）. The total effective rate based on TCM syndrome was 87.3% in the treatment group versus 73.0% in the control group, and the difference was statistically significant（P〈0.05）. There was a significant difference in comparing the DAS28 score between the two groups after intervention（P〈0.01）. Conclusion Electroacupuncture plus oral administration of Chinese medication and western medication is an effective approach in treating RA due to liver-kidney yin deficiency, and it can significantly enhance the therapeutic efficacy based on ACR20 and TCM syndrome.