超声心动图评价抗肿瘤药物心脏毒性的研究进展

Advancement of Echocardiography in Evaluation of Anti-cancer Drugs Induced Cardiac Toxicity

肿瘤已成为公共健康问题,抗肿瘤药物导致的心脏毒性极大地影响了患者的生存期及生活质量。超声心动图的经济、无创、普及性高等特点决定了其在评估抗肿瘤药物心脏毒性方面的重要作用,然而以左心室射血分数下降监测心脏毒性往往为时已晚。利用斑点追踪技术早期发现心脏毒性是目前研究的热点之一。现就超声心动图评估抗肿瘤药物心脏毒性的研究进展做一综述。

Cancer is a wide public health problem, however cardiotoxicity of chemotherapy has greatly affected the survival and quality of life of patients. Echocardiography is cost-effective, safe and widely available and as such it plays an important role in the detection of cardiotoxicity. Decline of the left ventricular ejection fraction is usually a late manifestation of cardiotoxicity. The application of speckle tracking echocardiography in the early detection of subclinical left ventricular dysfunction has already become a popular research topic. This was a review of the advancement of echocardiography in the evaluation of anticancer drugs induced cardiac toxicity.