活血祛瘀类中药配伍治疗慢性盆腔炎临床疗效观察

Curative Observation of Applying Traditional Chinese Medicine Compatibility of Activating Blood Circulation and Removing Blood Stasis in the Treatment of Chronic Pelvic Inflammatory Disease

目的：观察活血祛瘀类中药配伍结合西医治疗对慢性盆腔炎的疗效。方法：以2014年3月~2015年3月在我院接受治疗的80例慢性盆腔炎患者为观察对象,并将其随机分为对照组和观察组,每组各40例。对照组给予抗生素等西医治疗,观察组在此基础上给予活血祛瘀类中药配伍治疗,观察两组的治疗效果,比较两组治疗前后炎症细胞因子水平及血液流变学的变化。结果：观察组总有效率明显高于对照组,差别具有统计学意义;治疗前两组患者血常规及炎症因子水平无明显差别,治疗后两组WBC、NEU%、IL-6、hs-CRP和TNF-α均较治疗前降低,而观察组降低更为明显（P〈0.05）;两组治疗前血液流变学指标无明显差别,治疗后两组全血粘度、毛细管血浆粘度、全血还原粘度、红细胞聚集指数和纤维蛋白原水平均有所下降,而红细胞压积均有所升高,观察组上述指标改变较对照组更为明显。结论：活血祛瘀类中药配伍结合西医疗法可有效缓解炎症,对慢性盆腔炎有较好的治疗效果,可能与该疗法能改善患者的血液流变学特征有关。

Objective： To observe the effect of applying traditional Chinese medicine compatibility of activating blood circulation and removing blood stasis combined with western medicine therapy in treating chronic pelvic inflammatory. Methods： 80 cases with chronic pelvic inflammatory disease treated in our hospital from March 2014 to March 2015 were observed,and randomly divided into controlled group and observation group,40 cases in each group. The controlled group was given intravenous antibiotic treatment of western medicine,the observation group received blood stasis combined treatment of traditional Chinese Medicine. To observe the therapeutic effect of the two groups,compare the level of inflammatory cytokines and the changes of blood rheology before and after treatment of the two groups. Results： The total effective rate in the observation group was significantly higher than that in controlled group,and the difference was statistically significant. Before treatment,the level of routine blood and inflamma-tory factors in the two groups had no significant difference. The level of WBC,neu%,IL-6,hs-CRP and TNF-a in the two groups all decreased after treatment compared with those before treatment,while the observation group decreased more significantly（ P〈0. 05）. The two groups of patients before treatment showed no significant difference in blood rheology,after treatment,the level of whole blood viscosity,thin tube plasma viscosity,whole blood reduced viscosity,erythrocyte aggregation index and fibrinogen in the observation group were lower than the controlled group,and hematocrit was higher than the controlled group,the difference was statistical significance. Conclusions： Applying traditional Chinese medicine compatibility of activating blood circulation and removing blood stasis combined with western medicine therapy can effectively relieve inflammation,which has good therapeutic effect in the treatment of chronic pelvic inflammatory disease,and the therapy can improve the blood rheology in patients with characteristics.