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莫西沙星替代左氧氟沙星治疗耐多药肺结核疗效分析 被引量:11

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摘要 目的评价莫西沙星治疗耐多药肺结核的临床疗效。方法将67例耐多药肺结核患者随机分为治疗组和对照组,分别给予莫西沙星或左氧氟沙星联合卷曲霉素、对氨基水杨酸钠、丙硫异烟胺、吡嗪酰胺,比较两组临床疗效。结果治疗组在各个月痰菌阴转率均明显高于同期对照组(P﹤0.05);至治疗结束,痰菌涂片、培养检查,治疗组阴转率为81.0%,对照组阴转率为68.4%,治疗组明显高于对照组(P﹤0.05),差异有统计学意义。x线胸片或胸部CT检查:治疗组病灶吸收率和空洞闭合率有效率分别为80.6%和58.1%;对照组有效率分别为66.7%和43.3%,治疗组明显优于对照组(P﹤0.05),差异有统计学意义。结论含莫西沙星的治疗方案能明显提高耐多药结核病的痰菌阴转及病灶吸收、空洞闭合,且安全、可靠,值得临床推广应用。
出处 《疾病监测与控制》 2016年第9期756-757,共2页 Journal of Diseases Monitor and Control
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